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Table 2 Cox regression analysis of the identification of risk factors of hospital death within 90 days after intensive care unit admission

From: Association between serum levels of interleukin-6 on ICU admission and subsequent outcomes in critically ill patients with acute kidney injury

Variable

Adjusted risk ratio

95% confidence interval

P value

A. Analysis adjusted with APACHE II score

 Age

1.00

0.99–1.01

0.96

 Male sex

1.43

1.01–2.05

0.042

 Interleukin-6 level (per tertile)

1.09

0.88–1.35

0.42

 Chronic kidney disease

0.77

0.51–1.12

0.17

 APACHE II score

1.06

1.04–1.08

< 0.0001

 Etiology

  Cardiovascular disease

reference

  Sepsis

1.16

0.75–1.84

0.51

  All other etiologies

1.40

0.89–2.22

0.14

B. Analysis adjusted without APACHE II score

 Age

1.00

0.99–1.01

0.62

 Male sex

1.41

1.00–2.02

0.051

 Interleukin-6 level (per tertile)

1.28

1.04–1.58

0.018

 Chronic kidney disease

0.86

0.57–1.26

0.44

 Etiology

  Cardiovascular disease

reference

  Sepsis

0.87

0.57–1.36

0.53

  All other etiologies

1.05

0.68–1.66

0.83

  1. APACHE Acute physiology and chronic health evaluation
  2. Risk ratio associated with a one-unit change in age, interleukin-6 level (per tertile), and APACHE II score, and associated with positive findings for other variables