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Table 4 Multivariate logistic regression analysis of the identification of factors predictive of persistent acute kidney injury 90 days after intensive care unit admission or hospital discharge in survivors

From: Association between serum levels of interleukin-6 on ICU admission and subsequent outcomes in critically ill patients with acute kidney injury

Variable

Adjusted odds ratio

95% confidence interval

P value

A. Analysis adjusted with APACHE II score

 Age

1.02

1.00–1.03

0.010

 Male sex

1.01

0.64–1.58

0.98

 Interleukin-6 level (per tertile)

0.67

0.49–0.91

0.0097

 Chronic kidney disease

6.40

3.78–10.85

< 0.0001

 APACHE II score

1.02

1.00–1.05

0.10

 Etiology

  Cardiovascular disease

reference

  Sepsis

1.11

0.59–2.10

0.75

  All other etiologies

1.22

0.65–2.27

0.53

B. Analysis adjusted without APACHE II score

 Age

1.02

1.01–1.04

0.0058

 Male sex

1.00

0.64–1.57

0.99

 Interleukin-6 level (per tertile)

0.71

0.53–0.95

0.023

 Chronic kidney disease

6.66

3.94–11.26

< 0.0001

 Etiology

  Cardiovascular disease

reference

  Sepsis

0.95

0.52–1.76

0.88

  All other etiologies

1.06

0.58–1.93

0.84

  1. APACHE Acute physiology and chronic health evaluation
  2. Odds ratio associated with a one-unit change in age, interleukin-6 level (per tertile), and APACHE II score, and positive findings for other variables. Data were analyzed in 483 patients who survived 90 days or survived discharge before 90 days after intensive care unit admission