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Table 4 Renal outcome of unclear or drug-induced acute tubulointerstitial nephritis classified by steroid use

From: Effect of steroids and relevant cytokine analysis in acute tubulointerstitial nephritis

Outcome

All subjects (n = 102)

Non-treated group (n = 20)

Steroid-treated group (n = 82)

P-valuea

Matched steroid-treated group (n = 20)

P-value

Renal recovery at 6 months (%)

56.9

50.0

58.5

0.947

50.0

1.000

Renal recovery at last follow-up (%)

75.5

65.0

78.0

0.583

75.0

0.490

End-stage renal disease (%)

23.5

25.0

23.2

0.693

35.0

0.490

All-cause mortality (%)

15.7

20.0

14.6

0.248

10.0

0.661

  1. aAdjusted for age, sex, body mass index, diabetes mellitus, hypertension, chronic kidney disease, serum creatinine at kidney biopsy, uric acid, albumin, proteinuria, hematuria, tubular atrophy and interstitial fibrosis, leukocytes infiltration, and dialysis at biopsy