Table 2 Baseline associations of serum and dialysate electrolytes with QTc interval in 330 incident dialysis patients
Variables | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|
QTc difference (95% CI), ms | P | QTc difference (95% CI), ms | P | QTc difference (95% CI), ms | P | |
Serum measurements | ||||||
 Total calcium, per 1 mg/dl decrease | + 3.23 (−4.44, 10.89) | 0.41 | + 4.46 (− 2.84, 11.75) | 0.23 | + 2.70 (− 4.67, 10.06) | 0.47 |
 Corrected calcium, per 1 mg/dl decrease | + 2.27 (−6.48, 11.03) | 0.61 | + 3.46 (− 4.89, 11.80) | 0.42 | + 1.56 (− 6.65, 9.77) | 0.71 |
 Ionized calciuma, per 0.1 mmol/l decrease | + 9.77 (2.97, 16.57) | 0.01 | + 10.32 (3.87, 16.78) | 0.002 | + 8.55 (2.13, 14.97) | 0.01 |
 Potassium, per 1 mEq/l decrease | + 11.08 (2.18, 19.98) | 0.02 | + 10.97 (2.50, 19.43) | 0.01 | + 9.89 (1.58, 18.20) | 0.02 |
 Magnesiuma, per 0.1 mEq/l decrease | + 0.34 (− 1.73, 2.40) | 0.75 | + 0.35 (− 1.61, 2.31) | 0.73 | − 0.21 (− 2.13, 1.72) | 0.83 |
Dialysate measurements | ||||||
 Calcium | ||||||
  2.5 mEq/l | reference |  | reference |  | reference |  |
  < 2.5 mEq/l | + 1.27 (− 8.70, 11.24) | 0.80 | − 0.90 (− 10.55, 8.74) | 0.86 | + 0.95 (− 8.52, 10.42) | 0.84 |
 Potassium | ||||||
  2 mEq/l | reference |  | reference |  | reference |  |
  > 2 mEq/l | −2.73 (− 16.96, 11.49) | 0.71 | −3.53 (− 17.01, 9.94) | 0.61 | −3.98 (− 17.16, 9.21) | 0.56 |
Serum-to-dialysate gradients | ||||||
 Total calcium, per 1 mEq/l increase in difference | −3.33 (− 15.22, 8.55) | 0.58 | −6.84 (− 18.30, 4.62) | 0.24 | − 3.04 (− 14.57, 8.49) | 0.61 |
 Corrected calcium, per 1 mEq/l increase in difference | − 1.81 (− 14.66, 11.03) | 0.78 | − 5.40 (− 17.82, 7.02) | 0.40 | − 1.44 (− 13.72, 10.83) | 0.82 |