Clinical practice guideline monitoring children and young people with, or at risk of developing autosomal dominant polycystic kidney disease (ADPKD)

BMC Nephrology

Table 1 PICO characteristics

Population	Intervention	Comparison	Outcome	Study design
Children (< 18) with a confirmed diagnosis of ADPKD or at risk of ADPKD due to their family history	Ultrasonography Cranial imaging Blood Pressure monitoring Monitoring for albuminuria Therapeutics Genetic counselling	Any intervention compared with any other or no intervention	Mortality Hospitalisations Chronic Kidney Disease Cardiovascular disease Hypertension	Randomised controlled trials (RCT) Non-randomised studies if adjusted for key confounders (age, health at baseline, co-morbidities).