Fig. 3

Complement deposition on endothelial cells: Endothelial cells were incubated with a serum from the index patient and b control serum from a patient with acute complement-mediated TMA due to complement factor H mutation. Serum of the index patient caused no deposition of C3c (FITC) and C5b-9 (Rhodamine) on non-activated endothelial cells. Magnification × 40