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Table 3 Multivariate linear regression analyses for the relationship between serum potassium, transtubular potassium gradient, and urine angiotensinogen-creatinine ratio

From: Urinary angiotensinogen level is associated with potassium homeostasis and clinical outcome in patients with polycystic kidney disease: a prospective cohort study

Variables

Dependent variables

Serum potassium

TTKG

β

p-value

β

p-value

DM (vs. non-DM)

0.171

< 0.001

–

–

BMI (kg/m2)

−0.047

0.044

–

–

eGFR (mL/min/1. 73m2)

−0.315

< 0.001

0.157

< 0.001

Total CO2 (mmol/L)

−0.152

< 0.001

0.174

< 0.001

Serum albumin (g/dL)

0.066

0.019

–

–

UPCR (g/g)*

0.120

< 0.001

–

–

Urine AGT/Cr ratio (μg/g)*

− 0.058

0.017

0.087

0.001

Urine osmolality (mOsm/kg)*

− 0.056

0.046

0.118

< 0.001

Diuretics (vs. non-user)

  

–

–

Age (years)

–

–

0.104

< 0.001

Sex (vs. female)

–

–

0.139

< 0.001

Charlson comorbidity index

–

–

−1.000

0.002

  1. β: Standardized coefficient
  2. *Variables are log transformed
  3. Abbreviations: TTKG, trans-tubular potassium gradient; DM, diabetes mellitus; BMI, body mass index; eGFR, estimated glomerular filtration; CO2, carbon dioxide; UPCR, urine protein-to-creatinine ratio; AGT/Cr, angiotensinogen/creatinine