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Table 1 Changes in urinary protein, BUN and Scr in each group \( \overline{x}\kern0.5em \cdot \pm \kern0.5em s \), n = 10)

From: The role of podocyte damage in the etiology of ischemia-reperfusion acute kidney injury and post-injury fibrosis

  Group D8 D9 D10 D14 D28
UPE (mg/d) Ctr 1.47 ± 0.11 1.43 ± 0.18 1.45 ± 0.16 1.43 ± 0.14 1.46 ± 0.21
Sham 1.42 ± 0.18 1.49 ± 0.16 1.40 ± 0.15 1.42 ± 0.15 1.48 ± 0.20
AKI 20 1.43 ± 0.15 1.53 ± 0.24 1.48 ± 0.17 1.50 ± 0.12 1.52 ± 0.15
AKI 30 1.46 ± 0.13 1.86 ± 0.38 1.97 ± 0.22 3.64 ± 1.12* 10.88 ± 2.44**
AKI 40 1.38 ± 0.20 3.47 ± 0.63* 2.52 ± 0.26* 1.54 ± 0.33 1.55 ± 0.18
BUN (mmol/L) Ctr 11.41 ± 1.22 12.28 ± 1.01 10.99 ± 0.43 12.37 ± 1.29 10.93 ± 1.20
Sham 12.07 ± 1.31 10.92 ± 1.26 11.74 ± 0.55 12.49 ± 1.31 11.56 ± 1.47
AKI 20 11.89 ± 1.36 27.30 ± 2.32* 15.13 ± 1.11* 12.20 ± 1.24 11.12 ± 1.13
AKI 30 10.84 ± 1.47 28.48 ± 2.01* 17.36 ± 1.32* 25.45 ± 2.99*# 28.77 ± 1.23*#
AKI 40 12.35 ± 1.41 30.19 ± 2.62*# 25.27 ± 2.53*# 28.66 ± 1.78*# 37.48 ± 2.15*#Δ
Scr (umol/L) Ctr 7.41 ± 0.82 7.20 ± 0.81 6.91 ± 0.63 7.03 ± 0.72 6.89 ± 0.75
Sham 7.03 ± 0.71 7.19 ± 0.98 7.17 ± 0.81 6.99 ± 0.76 7.11 ± 0.87
AKI 20 7.12 ± 0.80 16.39 ± 1.84* 13.88 ± 1.21* 7.78 ± 1.26 7.35 ± 1.18
AKI 30 7.81 ± 0.67 16.72 ± 1.56* 12.96 ± 1.43* 15.26 ± 1.29*# 22.34 ± 1.17*#
AKI 40 7.39 ± 0.88 16.58 ± 2.07*# 23.22 ± 2.38*# 28.97 ± 2.92*#Δ 28.04 ± 1.09*#Δ
  1. UPE, urinary protein excretion; BUN, blood urea nitrogen; Scr, serum creatinine. *P < 0.05 vs Ctr, **P < 0.01 vs Ctr, #P < 0.05 vs AKI 20, ΔP < 0.05 vs AKI 30