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Table 1 Patient demographics

From: Living-donor transplantation leads to a major improvement in physical functioning: an observational study on the impact on potential donors and their recipients

Pre-surgery

Recipients

Donors

Number of Patients

21

22

Male/Female (%)

47.6 / 52.4

36.4 / 63.6

Age (years)

54.1 ± 12.5

55.5 ± 10.6

Height (cm)

173.1 ± 10.4

171.6 ± 7.6

Weight (kg)

73.8 ± 17.3

81.3 ± 15.7

BMI (kg/m2)

24.5 ± 4.5

27.5 ± 4.6

FO (L)

0.5 ± 1.8

−0.2 ± 1.3 (n = 21c)

Cause of end-stage renal disease

Diabetic nephropathy (%)

9.5 (n = 2)

-

Polycystic kidney disease (%)

23.8 (n = 5)

 

Nephrosclerosis (%)

4.8 (n = 1)

 

Hypertensive nephropathy (%)

19.0 (n = 4)

 

IgA nephropathy (%)

14.3 (n = 3)

 

Unknown cause (%)

4.8 (n = 1)

 

Other (%)

23.8 (n = 5)

 

Diabetes Mellitus (%)

14.3 (n = 3)

0

Cardiovascular Disease (%)a

14.3 (n = 3)

13.6 (n = 3)b

eGFR (ml/min/1.73m2)

8.7 ± 3.6

85.7 ± 11.8

Albumin (g/L)

36.7 ± 4.7

40.4 ± 4.0 (n = 20c)

C-reactive protein (mg/L)

5.0 ± 5.7

2.7 ± 3.2 (n = 20c)

Hemoglobin (mmol/L)

7.5 ± 0.9

8.9 ± 0.9 (n = 16c)

Total CO2 (mmol/L)

27.1 ± 2.9

–

Previous transplant (%)

14.3 (n = 3)

–

Pre-emptive transplant (%)

42.9 (n = 9)

–

Pre-KTx HD/PD

6/6

–

SBP (mmHg)

149.6 ± 24.4

140.3 ± 19.9

DBP (mmHg)

86.3 ± 12.4

86.8 ± 12.3

Post-surgery

 eGFR (ml/min/1.73m2)

(n = 17c)

 

 1 month post-surgery

45.1 ± 11.5

–

 3 months post-surgery

48.1 ± 10.4

58.8 ± 11.1 (n = 18c)

 6 months post-surgery

52.2 ± 9.6

–

 12 months post-surgery

53.9 ± 8.7

54.5 ± 8.8 (n = 15c)

 Hemoglobin (mmol/L)

(n = 16c)

n/a

 1 month post-surgery

6.8 ± 1.3

 

 3 months post-surgery

7.5 ± 1.2

 

 6 months post-surgery

8.2 ± 1.1

 

 12 months post-surgery

7.9 ± 2.2

 

Blood pressure (mmHg)

SBP

DBP

SBP

DBP

(n = 17c)

(n = 17c)

(n = 18c)

(n = 18c)

1 month post-surgery

148.6 ± 25.9

86.9 ± 11.8

–

–

3 months post-surgery

134.2 ± 21.1

84.5 ± 15.4

132.7 ± 21.5

87.1 ± 11.1

6 months post-surgery

139.8 ± 16.7

86.2 ± 14.0

–

–

12 months post-surgery

138.5 ± 16.4

82.6 ± 11.2

135.6 ± 27.1

86.7 ± 12.8

  1. Data are presented as mean ± SD
  2. BMI body mass index, FO fluid overload, SBP systolic blood pressure, DBP diastolic blood pressure, eGFR estimated glomerular filtration rate
  3. aHypertension is excluded, bCVD diagnoses in kidney transplant donors included infrarenal aortic abdominal aneurysm (n = 1), and transient ischemic attack (n = 2), c Data available in number of patients (n=)