Fig. 4

Association between the reporting of an item as a disadvantage and: a subsequent hazard of death, HD transition, or both; and (b) measures of poor QOL and depression for each of the eight items, in which more than 10% of patients scored that item as a disadvantage of PD. The reference group consisted of patients who reported the item as an advantage or neutral. PCS and MCS scores were derived from the SF-12, with lower scores indicating worse QOL, and depressive symptoms were assessed by the 10-item version of the CES-D, where CES-D ≥ 10 was a positive screen for depressive symptoms. All models adjusted for the following potential confounders: age, sex, BMI, time on PD, 13 summary comorbid conditions (Table 1), serum albumin, 24-h urine volume, and previous HD treatment. Models for: a were stratified by country and US LDO; and for (b) were additionally adjusted for country and US LDO. Abbreviations: ADS advantage/disadvantage score, BMI body mass index, CES-D Center for Epidemiological Studies Depression Screening Index, CI confidence interval, HD hemodialysis, HR hazard ratio, LDO large dialysis organization, MCS mental component summary, PCS physical component summary, PD peritoneal dialysis, QOL quality of life, SF short form, US United States