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Table 5 Correlation of various parameters with hypothesized associations with circulating vitamin C levels

From: The effect of increased frequency of hemodialysis on vitamin C concentrations: an ancillary study of the randomized Frequent Hemodialysis Network (FHN) daily trial

Correlations with Vitamin C Concentrations (Natural Log Transformed)

Statistic / Grouping

CRP (mg/L) -natural log transformation

Predialysis hemoglobin (mg/dL)

Equilibrated per session Kt/V urea

ePCR (g/kg/d)

Predialysis Parathyroid hormone

Physical Health Composite score

Dialysis weekly standard Kt/V

Pearson correlation (complete cohort)

−0.10 (P = 0.59)

[N = 34]

0.32 (P = 0.03)

[N = 44]

− 0.05 (P = 0.77)

[N = 44]

0.19 (P = 0.21)

[N = 44]

− 0.31 (P = 0.04)

[N = 44]

0.12 (P = 0.44)

[N = 44]

− 0.07 (P = 0.64)

[N = 44]

3×, Pearson correlation

−0.15 (P = 0.58)

[N = 16]

0.35 (P = 0.13)

[N = 20]

−0.07 (P = 0.78)

[N = 20]

0.21 (P = 0.37)

[N = 20]

−0.31 (P = 0.19)

[N = 20]

0.35 (P = 0.13)

[N = 20]

− 0.16 (P = 0.49)

[N = 20]

6×, Pearson correlation

−0.08 (P = 0.76)

[N = 18]

0.38 (P = 0.07)

[N = 24]

−0.10 (P = 0.66)

[N = 24]

0.12 (P = 0.58)

[N = 24]

−0.36 (P = 0.09)

[N = 24]

−0.21 (P = 0.32)

[N = 24]

+ 0.07 (P = 0.76)

[N = 24]

Spearman correlation (complete cohort)

−0.19 (P = 0.28)

[N = 34]

0.34 (P = 0.02)

[N = 44]

−0.08 (P = 0.63)

[N = 44]

0.19 (P = 0.23)

[N = 44]

−0.16 (P = 0.30)

[N = 44]

0.10 (P = 0.52)

[N = 44]

− 0.12 (P = 0.43)

[N = 44]

3×, Spearman correlation

−0.31 (P = 0.25)

[N = 16]

0.33 (P = 0.16)

[N = 20]

−0.16 (P = 0.50)

[N = 20]

0.09 (P = 0.70)

[N = 20]

0.11 (P = 0.63)

[N = 20]

0.47 (P = 0.04)

[N = 20]

− 0.31 (P = 0.19)

[N = 20]

6×, Spearman correlation

−0.07 (P = 0.77)

[N = 18]

0.30 (P = 0.16)

[N = 24]

−0.10 (P = 0.66)

[N = 24]

0.12 (P = 0.58)

[N = 24]

−0.40 (P = 0.06)

[N = 24]

−0.22 (P = 0.30)

[N = 24]

+ 0.04 (P = 0.86)

[N = 24]