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Table 1 PCA/multivariate Analysis models for plasma

From: Meprin β metalloproteases associated with differential metabolite profiles in the plasma and urine of mice with type 1 diabetes and diabetic nephropathy

  Model # of Compounds Total # Samples # of Components R2X R2Y Q2 # Samples in STZ # Samples in NaC
Positive PCA All Samples 2414 62 7 0.947   0.85   
PCA 4 wks 2414 28 7 0.96   0.841   
PCA WT STZ v WT NaC 4 wk 2414 14 4 0.937   0.759   
OPLSDA WT STZ v WT NaC 4 wk 2414 14 1 + 1 0.75 0.619 0.0699 9 5
PCA βKO STZ v βKO NaC 4wk 2414 14 4 0.93   0.756   
OPLSDA βKO STZ v βKO NaC 4wk 2414 14 1 + 3 0.908 0.956 0.788 8 6
PCA 8 wks 2414 28 5 0.942   0.834   
PCA WT STZ v WT NaC 8 wk 2414 13 5 0.967   0.829   
OPLSDA WT STZ v WT NaC 8 wk 2414 13 1 + 2 0.845 0.912 0.764 8 5
PCA βKO STZ v βKO NaC 8wk 2414 14 4 0.962   0.912   
OPLSDA βKO STZ v βKO NaC 8wk 2414 14 1 + 7 0.984 1 0.731 8 6
Negative PCA All Samples 633 57 8 0.877   0.711   
PCA 4 wks 633 25 3 0.76   0.385   
PCA WT STZ v WT NaC 4 wk 633 12 4 0.925   0.558   
OPLSDA WT STZ v WT NaC 4 wk 633 12 1 + 2 0.873 0.962 0.876 7 5
PCA βKO STZ v βKO NaC 4wk 633 13 2 0.58   0.23   
OPLSDA βKO STZ v βKO NaC 4wk 633 13 1 + 1 0.528 0.958 0.876 7 6
PCA 8 wk 633 26 3 0.759   0.478   
PCA WT STZ v WT NaC 8 wk 633 12 3 0.866   0.497   
OPLSDA WT STZ v WT NaC 8 wk 633 12 1 + 2 0.861 0.973 0.907 7 5
PCA βKO STZ v βKO NaC 8wk 633 14 3 0.759   0.174   
OPLSDA βKO STZ v βKO NaC 8wk 633 14 1 + 1 0.498 0.871 0.686 8 6
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