4 Weeks post STZ | 8 weeks Post STX | |||||||
---|---|---|---|---|---|---|---|---|
Metabolite | VIP | P-value* | FC** | Metabolite | VIP | P-value* | FC** | |
WT Only | 3-Methoxy-4-hydroxyphenylethyleneglycol sulfate | 0.7 | 0.003 | 6.6 | 3-Methoxy-4-hydroxyphenylethyleneglycol sulfate | 0.5 | 0.01 | 9.1 |
N-Heptanoylglycine | 0.6 | 0.005 | -5.2 | 3-Aminosalicylic acid | 0.9 | 0.045 | 3.6 | |
3-Methoxytyrosine | 0.5 | 0.018 | −3.8 | LysoPC(16:1(9Z)) | 3 | 0.019 | −3.6 | |
7-Methoxy-5-prenyloxycoumarin | 0.6 | 0.042 | 2 | 5-Acetyl-2,4-dimethyloxazole | 0.4 | 0.003 | 3.1 | |
Guanine | 0.3 | 0.019 | 2.7 | |||||
Taurocholic acid | 3.2 | 0.019 | 2.5 | |||||
9′-Carboxy-gamma-chromanol | 0.5 | 0.019 | 2.5 | |||||
Riboflavin | 0.4 | 0.019 | 2.5 | |||||
N-Acetylleucine | 1 | 0.005 | 2.2 | |||||
Indoxyl sulfate | 5.3 | 0.003 | 2.1 | |||||
2-Phenylglycine | 0.3 | 0.003 | 2.1 | |||||
N-Heptanoylglycine | 0.2 | 0.03 | −2.1 | |||||
7-Methoxy-5-prenyloxycoumarin | 0.4 | 0.019 | 2 | |||||
βKO Only | Porric acid B | 0.5 | 0.021 | 3.7 | Isovalerylalanine | 0.7 | 0.016 | −2.5 |
3-Methoxy-4-hydroxyphenylethyleneglycol sulfate | 1.7 | 0.047 | 3.3 | |||||
L-Acetylcarnitine | 1 | 0.021 | 3.1 | |||||
D-1,5-Anhydrofructose | 0.8 | 0.01 | −3.1 | |||||
Hexanoylcarnitine | 0.5 | 0.042 | −2.2 | |||||
N-Acetylleucine | 1 | 0.021 | 2 | |||||
Tyrosyl-Valine | 0.3 | 0.016 | 2 |