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Table 2 Treatments of ANCA-associated vasculitis complicated with thymoma (review)

From: Microscopic polyangiitis associated with thymic tumor: a case report and review of the literature

No.

authors

year

thymectomy

thymic pathology

medication for vasculitis

outcome

findings

class

CS

CYC

others

remission

relapse

1

Haberhauer G, et al.

1993

done

hyperplasia

 

+

–

NSAID

CR

relapse

2

Kobayashi M, et al.

1995

done

non-invasive

B2

30 mg/d

–

G-CSFa

CRa

none

3

Valli G, et al.

1998

done

NA

NA

+

+

–

ESRD

NA

4

Karras A, et al.

2005

done

non-invasive

B2

+

–

AZA

CR

NA

5

Karras A, et al.

2005

not done

  

+

–

–

PR

NA

6

Parambil JG, et al.

2006

done

non-invasive

B2

1.0 mg/kg/d

2.0 mg/kg/d

AZA

CR

none

7

Holmes MV, et al.

2007

done

invasive

B1

+

+

–

CR

NA

8

The present case

2018

not done

  

1.0 mg/kg/d

–

Rituximab

ESRD

none

  1. CS corticosteroid, CYC cyclophosphamide, NSAID non-steroidal anti-inflammatory drugs, G-CSF granulocyte-colony stimulating factor, AZA azathioprine, CR complete remission, PR partial remission, ESRD end-stage renal disease, NA not available
  2. aMedications and prognosis for granulocytopenia