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Table 3 Potential predictors of successful discontinuation collected on day 2

From: Predictors of short-term successful discontinuation of continuous renal replacement therapy: results from a prospective multicentre study

 

All patients n = 92

Successful stop CRRT n = 61 (66%)

Unsuccessful stop CRRT n = 31 (34%)

P-value

Primary study variables

 Urine output (L)

2.160 (1.276)

2.424 (1.232)

1.640 (1.217)

0.005

 Creatinine clearance, ml/min

20 [7, 41]

29 [14, 56]

7 [4, 16]

< 0.001

 Creatinine ratio (day 2/ day 0)

1.35 [1.06, 1.63]

1.16 [0.91, 1.39]

1.63 [1.42, 1.81]

< 0.001

 Urinary NGAL (ng/ml)/ creatinine (mmol/L) (n = 63)

152 [15, 601]

80 [10, 249]

583 [203, 1027]

0.002

 Vasopressor use, nr (%)

22 (24)

10 (16)

12 (39)

0.018

 Non-renal SOFA score

4 [3, 7]

4 [3, 5]

6 (3)

0.080

Secondary study variables

 Duration of CRRT (days)

5 [3, 10]

4 [3, 9]

7 [4, 17]

0.014

 Cumulative fluid balance, day 0–2 (L)

−0.430 (3.129)

−1.284 (2.884)

1.250 (2.942)

< 0.001

  1. Mean (standard deviation) for normally distributed variables, median [25th and 75th percentile] for non-normally distributed variables, number (percentage) when appropriate
  2. NGAL neutrophil gelatinase-associated lipocalin, SOFA sequential organ failure assessment, CRRT continuous renal replacement therapy