Predictors of short-term successful discontinuation of continuous renal replacement therapy: results from a prospective multicentre study

Table 4 Univariate analysis of variables associated with successful discontinuation (n = 92)

	OR	95% CI	P-value
Primary study variables
Urine output (L) (day 2)	1.777	1.168–2.704	0.007
Creatinine clearance, ml/min (day 2)	1.069	1.030–1.109	< 0.001
Creatinine ratio (day 0 / day2)	0.100	0.027–0.370	0.001
Urinary NGAL (ng/ml)/creatinine (mmol/L) (day 2) (n = 63)	0.998	0.997–1.000	0.025
Vasopressor use (day 2)	0.310	0.115–0.836	0.021
Non-renal SOFA score (day 2)	0.854	0.729–1.001	0.052
Secondary study variables
Duration of CRRT (days)	0.926	0.868–0.987	0.018
Cumulative fluid balance, day 0–2 (L)	0.734	0.618–0.876	0.001

OR Odds ratio; The odds ratios are per unit increase, 95% CI 95% confidence interval, NGAL neutrophil gelatinase-associated lipocalin, SOFA sequential organ failure assessment, CRRT continuous renal replacement therapy

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