Fig. 4
From: Increased ENaC activity during kidney preservation in Wisconsin solution
ENaC expression and activity in dog kidney after preservation in UW solution. a Current traces from a representative cell-attached patch that contained ENaC. This patch was formed on the apical membrane of a principal cell in an isolated split-open collecting duct that was isolated from dog kidney. The holding membrane potential is − 60 mV. “c” and “o” denote closed and open current levels, respectively. b Summary graph of ENaC activity (NPo) and channel open probability (Po) indicates high channel activity in dog kidneys preserved in UW solution for 24 h. c Representative images of immunohistochemical staining of β-ENaC (shown in brown) in dog kidney cortical sections