Skip to main content

Table 2 ROC curve of serum IgG, IgA, IgM, C3, C4 and IgA/C3 ratio in predicting IgAN

From: High serum IgA/C3 ratio better predicts a diagnosis of IgA nephropathy among primary glomerular nephropathy patients with proteinuria ≤ 1 g/d: an observational cross-sectional study

 

Full cohort

 

PSM cohort

Area

P

Cut-off point

Sensitivity

(%)

Specificity

(%)

Youden index

Area

P

Cut-off point

Sensitivity

(%)

Specificity

(%)

Youden index

IgG

0.810

< 0.001

8.32

77.85

76.63

0.5448

0.629

< 0.001

8.32

58.13

68.63

0.2676

IgA

0.715

< 0.001

2.245

70.45

63.61

0.3415

0.696

< 0.001

2.12

74.51

56.37

0.3088

IgM

0.587

< 0.001

1.31

49.01

66.86

0.1587

0.580

0.005

1.20

54.90

61.76

0.1667

C3

0.657

< 0.001

1.081

66.84

60.06

0.2690

0.621

< 0.001

1.08

64.71

61.27

0.2598

C4

0.628

< 0.001

0.25

57.12

65.09

0.2221

0.558

0.044

0.25

49.50

63.24

0.1274

IgA/C3 ratio

0.767

< 0.001

2.102

75.03

67.46

0.4249

0.734

< 0.001

2.410

58.82

77.45

0.3627

  1. C3 complement 3, C4 complement 4, IgA immunoglobulin A, IgAN immunoglobulin A nephrology, IgG immunoglobulin G, IgM immunoglobulin M, PSM propensity score matched, ROC receiver operating characteristic
Back to article page

BMC Nephrology

ISSN: 1471-2369

Contact us