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Table 3 ROC curve of IgA/C3 ratio in predicting IgAN in different proteinuria levels

From: High serum IgA/C3 ratio better predicts a diagnosis of IgA nephropathy among primary glomerular nephropathy patients with proteinuria ≤ 1 g/d: an observational cross-sectional study

 

Full cohort

 

PSM cohort

Area

P

Cut-off point

Sensitivity

(%)

Specificity

(%)

Youden index

Area

P

Cut-off point

Sensitivity

(%)

Specificity

(%)

Youden index

Proteinuria ≤1 g/d

0.801

< 0.001

2.229

70.75

80.85

0.5160

0.803

< 0.001

2.352

66.67

82.98

0.4965

Proteinuria 1–3.5 g/d

0.726

< 0.001

2.458

64.32

73.47

0.3779

0.717

< 0.001

1.977

80.77

55.17

0.3594

Proteinuria > 3.5 g/d

0.688

< 0.001

1.833

74.29

59.16

0.3345

0.704

< 0.001

2.013

65.22

70.00

0.3522

  1. C3 complement 3, IgA immunoglobulin A, IgAN immunoglobulin A nephrology, PSM propensity score matched, ROC receiver operating characteristic
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BMC Nephrology

ISSN: 1471-2369

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