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Table 4 ROC curve for serum IgA/C3 ratio in predicting IgAN in different renal function

From: High serum IgA/C3 ratio better predicts a diagnosis of IgA nephropathy among primary glomerular nephropathy patients with proteinuria ≤ 1 g/d: an observational cross-sectional study

 

Full cohort

 

PSM cohort

Area

P

Cut-off point

Sensitivity

(%)

Specificity

(%)

Youden index

Area

P

Cut-off point

Sensitivity

(%)

Specificity

(%)

Youden index

CDK 1 stage

0.769

< 0.001

2.097

72.03

69.09

0.4112

0.719

< 0.001

2.578

54.08

81.52

0.3560

CKD 2 stage

0.788

< 0.001

2.229

72.10

74.68

0.4689

0.779

< 0.001

1.7521

92.00

51.35

0.4335

CKD 3–5 stage

0.703

< 0.001

1.977

84.98

56.90

0.4187

0.688

< 0.001

1.977

83.93

60.53

0.4445

  1. C3 complement 3, CKD chronic kidney disease, IgA immunoglobulin A, IgAN immunoglobulin A nephrology, PSM propensity score matched, ROC receiver operating characteristic