| OR (95% CI) | P Value |
---|
Model 1 R2 = 0.233 |
IgA/C3 ratio (per 1) | 2.676 (2.268–3.158) | < 0.001 |
Model 2 R2 = 0.229 |
Age (per 1 year) | 0.952 (0.941–0.962) | < 0.001 |
IgA/C3 ratio (per 1) | 2.742 (2.307–3.260) | < 0.001 |
Model 3 R2 = 0.360 |
Age (per 1 year) | 0.936 (0.923–0.948) | < 0.001 |
IgG (per 1 mmol/L) | 1.385 (1.315–1.458) | < 0.001 |
IgA/C3 ratio (per 1) | 2.051 (1.702–2.471) | < 0.001 |
Model 4 R2 = 0.466 |
Age (per 1 year) | 0.932 (0.918–0.947) | < 0.001 |
Albumin (per 1 g/L) | 1.198 (1.171–1.226) | < 0.001 |
CKD stage |
CKD2 (versus CKD1) | 2.278 (1.407–3.687) | 0.001 |
CKD3–5 (versus CKD1) | 4.782 (2.766–8.269) | < 0.001 |
IgA/C3 ratio (per 1) | 2.159 (1.759–2.650) | < 0.001 |
- Model 1: IgA/C3 ratio, univariate
- Model 2: IgA/C3 ratio, age and gender (male = 1; female = 2) adjusted
- Model 3: IgA/C3 ratio, age, gender (male = 1; female = 2), IgG, IgA, IgM, C3, C4 adjusted
- Model 4: multivariable adjusted
- Variables of univariate regression analysis include age, gender (male = 1, female = 2), course, clinic-SBP, clinic-DBP, BMI, hematuria, Lg (proteinuria), proteinuria stage, hemoglobin, albumin, uric acid, serum cystatin, blood urea nitrogen, serum creatinine, eGFR-MDRD, CKD stage, IgG, IgA, IgM, C3, C4 and IgA/C3 ratio
- All variables with significant associations in univariate regression analysis were included in Model 4 multivariate regression analysis
- BMI body mass index, C3 complement 3, C4 complement 4, CI confidence interval, CKD chronic kidney disease, DBP diastolic blood pressure, eGFR estimated glomerular filtration rate, HDL-C high-density lipoprotein cholesterol, IgA immunoglobulin A, IgAN immunoglobulin A nephrology, IgG immunoglobulin G, IgM immunoglobulin M, LDL-C low-density lipoprotein cholesterol, OR odds ratio, PSM propensity score matched, SBP systolic blood pressure