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Table 4 Risk factors for chronic kidney disease during antiretroviral therapy

From: Chronic kidney disease and HIV in the era of antiretroviral treatment: findings from a 10-year cohort study in a west African setting

 

HR

CI95%

p-value

Baseline age (years)

Ref (< 40)

–

–

–

40–49

4.2

[1.6;11.2]

0.004

≥50

4.5

[1.5;14.1]

0.009

Baseline high blood pressure

4.3

[1.8;9.9]

0.001

cART exposure

AZT without PI

–

–

–

AZT + PI

0.5

[0.1;4.2]

0.542

TDF without PI

1.6

[0.6;4.2]

0.347

TDF + PI

2.3

[0.5;10.4]

0.300

d4T without PI

2.0

[0.4;9.8]

0.393

d4T + PI

6.7

[0.8;55.9]

0.079

ABC/ddI

13.1

[4.0;42.9]

< 0.001

  1. HR hazard ratio, CI confidence interval, cART combination Antiretroviral Therapy, AZT Zidovudine, PI protease inhibitor, TDF Tenofovir Disoproxil Fumarate, d4T Stavudine, ABC abacavir, ddI didanosine