Fig. 2From: Clinical significance of C4d deposition in renal tissues from patients with primary Sjögren’s syndrome—a preliminary studyRenal pathology and C4d deposition in kidney tissues from patients with pSS related renal impairments. pSS renal impairments (light microscopy, IHC). Tubulointerstitial C4d and peritubular capillary C4d staining were semi-quantitatively scored from 1 to 3. A1 × 200, pSS-related MN, C4d continuous staining along GBM and mild staining in mesangium(arrow). A2 × 200, pSS-related MN, C4d segmental staining along GBM. A3 × 100, pSS-related IgAN, mild mesangial staining of C4d which did not meet the criteria for G-C4d+, mesangial deposition of IgA and C3 positive. B1 × 200, TI-C4d score 1. Clinically dRTA, TIN, IF(−). B2 × 200, TI-C4d score 2. Clinically dRTA, TIN, IF(−). B3 × 200, TI-C4d score 3. Clinically RTA, TIN+mild MePGN, glomerular IF(−), interstitial C3 deposition positive by IF. C1 × 200, PTC C4d score 1(minimal staining). TIN+MePGN, IF(−). C2 × 200, PTC C4d score 2(focal staining). Early MN, with IgG(3+), IgA(2+) and C3(3+) deposition along GBM, C1q negative. C3 × 200, PTC-C4d score 3(diffuse staining). TINBack to article page