Items | Total (n = 39) | TIN (n = 21) | GMN (n = 18) | P |
---|---|---|---|---|
Age at KB (years, M ± SD) | 42 ± 14.1 | 36 ± 12.5 | 48 ± 13.5 | 0.008 |
Male:female ratio | 9/30 | 3/18 | 6/12 | NS |
PSS duration (years, IQR) | 5.0 [2.0, 16.0] | 3.0 [1.75, 7.50] | 11.5 [2.0, 20.0] | 0.025 |
IS therapy (%) | 15/39 (38.5) | 8/21 | 7/18 | NS |
ANA (+) (%) | 37/39 (94.9) | 21/21 | 16/18 | NS |
ANA 1:1280 (+) (%) | 8/39 (20.5) | 5/21 | 3/18 | NS |
ANA 1:640 (+) (%) | 16/39 (41.0) | 11/21 | 5/18 | NS |
Anti-SSA (+) (%) | 34/39 (87.2) | 18/21 | 16/18 | NS |
Anti-SSB (+) (%) | 13/39 (33.3) | 9/21 | 4/18 | NS |
Serum IgG elevation (%) | 25/38 (65.8) | 17/20 | 8/18 | 0.016 |
Serum IgA elevation (%) | 14/38 (36.8) | 6/20 | 8/18 | NS |
Serum IgM elevation (%) | 4/38 (10.5) | 3/20 | 1/18 | NS |
HypocomplementemiaLow CH50 | 3/38 (7.9) | 0/20 | 3/18 | NS |
Low C3 | 6/38 (15.8) | 1/20 | 5/18 | NS |
Low C4 | 6/35 (17.1) | 2/17 | 4/18 | NS |
RTA(%) | 22/39 (56.4) | 20/21 | 2/18 | < 0.001 |
Urinary calcification/stone (%) | 12/39 (30.8) | 10/21 | 2/18 | 0.018 |
Microhaematuria (%) | 18/39 (46.2) | 5/21 | 13/18 | 0.004 |
Proteinuria (%) | ||||
Mild (< 1.5 g/day) | 25/39 (64.1) | 17/21 (81.0) | 8/18 (44.4) | |
Moderate (1.5–3.5 g/day) | 7/39 (17.9) | 4/21 (19.0) | 3/18 (16.7) | 0.006 |
Nephrotic range (> 3.5 g/day) | 7/39 (17.9) | 0/21 (0) | 7/18 (38.9) | |
24-h urine collection (g/day, M ± SD) | 2.2 ± 3.7 | 0.8 ± 0.6 | 3.9 ± 4.9 | 0.033 |
Scr (μmol/L, M ± SD) | 103.9 ± 40.99 | 113.2 ± 42.33 | 93.0 ± 37.60 | NS |
eGFR (mL/min.1.73 m2, M ± SD) | 70.2 ± 27.23 | 64.0 ± 28.17 | 77.5 ± 24.90 | NS |