Table 2 Effect of hypertonic saline and furosemide on plasma concentrations of electrolytes in a randomized, cross-over study of 24 healthy subjects

 Placebo

140 ± 2

144 ± 2^*

141 ± 2^*

0.073

 Furosemide

139 ± 2

144 ± 2^*

141 ± 2^*

 Placebo

3.8 ± 0.2

3.7 ± 0.2^*

4.0 ± 0.2^*

0.001

 Furosemide

3.7 ± 0.2

3.5 ± 0.2^{*, †}

3.8 ± 0.2^†

 Placebo

105 ± 2

111 ± 2^*

107 ± 2^*

< 0.001

 Furosemide

104 ± 2

108 ± 2^{*, †}

104 ± 2^{*, †}

 Placebo

282 ± 4

289 ± 3^*

286 ± 4^*

0.034

 Furosemide

282 ± 3

291 ± 3^{*, †}

286 ± 3^*

 Placebo

27 ± 2

25 ± 2^*

25 ± 2^*

 Furosemide

26 ± 2

26 ± 2^†

27 ± 2^†