Effect of deflazacort on pregnancy outcome in kidney transplant patients: should we change the immunosuppressant before conception?

Table 5 Adjusted odds ratios of immunosuppressants in clinical pregnancy

Immunosuppressant	Unadjusted OR (95% CI)	P value	Adjusted OR (95% CI)	P value
CyA	2.1 (0.55–8.0)	0.28	1.38 (0.22–8.89)	0.73
TAC	0.62 (0.17–2.25)	0.46	0.84 (0.16–4.49)	0.84
DFZ	0.09 (0.02–0.53)	0.007	0.06 (0.01–0.68)	0.02
Pred	2.23 (0.63–7.93)	0.21	2.8 (0.53–14.85)	0.23
Aza	0.29 (0.05–1.75)	0.18	0.48 (0.06–4.1)	0.5
MMF	0.88 (0.19–4.16)	0.88	0.78 (0.14–4.39)	0.78

The P-values were obtained using simple and multiple logistic regression analysis. The analysis was adjusted for age, estimated glomerular filtration rate, graft rejection after transplantation, diabetes mellitus, and use of assisted reproductive techniques. The logistic regression analysis was performed for each immunosuppressant, respectively
Note: CyA, cyclosporine; TAC, tacrolimus; DFZ, deflazacort; Pred, predinosolone; Aza, azathioprine; MMF, mycophenolate mofetil; OR, odds ratio; CI, confidence interval

ISSN: 1471-2369