Table 4 Outcome of sequential alternative immunosuppressive therapies in children with DNS
Response to levamisole in children with FR/SD(n = 55) | |||
Outcome N (%) | FR 41 (74.54%) | SD 14 (25.46) | Total 55 (100) |
Effective | 34 | 10 | 44 (80) |
Not effective | 7 | 4 | 11 (20) |
Response to cyclophosphamide in children with DNS (n = 90) | |||
Outcome N (%) | FR/SD 70 (77.77) | SRNS 20 (22.22) | 90 (100) |
Complete remission | 45 | 07 | 52 (57.77) |
Partial remission | 13 | 07 | 20 (22.22) |
Resistant | 12 | 06 | 18 (20) |
Response to cyclosporin in children with DNS (n = 88) | |||
Outcome N (%) | FR/SD 49 (55.68) | SRNS 39 (44.31) | 88 (100) |
Complete remission | 30 | 11 | 41 (46.59) |
Partial remission | 18 | 17 | 35 (39.72) |
Resistant | 1 | 11 | 12 (13.63) |
Response to mycophenolate mofetil in children with DNS (n = 39) | |||
Outcome N (%) | FR/SD 21 (53.84) | SRNS 18 (46.15) | 39 (100) |
Complete remission | 4 | 1 | 5 (12.82) |
Partial remission | 16 | 11 | 27 (69.23) |
Resistant | 7 | 6 | 13 (33.33) |
Response to combination of CS and MMF in children with DNS (n = 20) | |||
Outcome N (%) | FR/SD 12 (60) | SRNS 8 (40) | 20 (100) |
Complete remission | 4 | 2 | 6 (30) |
Partial remission | 7 | 5 | 12 (60) |
Resistant | 1 | 1 | 2 (10) |
CS dependenta | 9 | 6 | 15 (17.04) |