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Table 2 Baseline characteristics of the RENIS-T6 participants according to mGFR-quartiles, n = 1627

From: Low-grade impairments in cognitive and kidney function in a healthy middle-aged general population: a cross-sectional study

 

Quartile of glomerular filtration rate, range (ml/min/1.73 m2)

 

Quartile 1

Quartile 2

Quartile 3

Quartile 4

(21.9–82.8)

(82.8–91.5)

(91.5–101.2)

(101.2–138.6)

N (%)

407 (25.0)

407 (25.0)

407 (25.0)

406 (25.0)

Female, n (%)

283 (69.5)

221 (54.3)

193 (47.4)

129 (31.8)a

Age, years

59.2 ± 3.5

58.2 ± 3.8

57.6 ± 3.9

57.3 ± 3.9a

Height, cm

169.3 ± 8.6

170.5 ± 8.5

170.8 ± 9.1

172.0 ± 8.6a

Body weight, kg

78.8 ± 14.1

78.9 ± 14.1

79.7 ± 14.6

81.4 ± 14.6b

Body mass index, kg/m2

27.5 ± 4.4

27.1 ± 4.0

27.2 ± 3.7

27.4 ± 3.8

Daily smoking, n (%)

77 (19.0)

71 (17.5)

80 (19.7)

116 (28.6)b

Use of alcohol > 2–4 times a month, n (%)

112 (27.7)

116 (28.6)

99 (24.4)

115 (28.3)

LDL cholesterol, mmol/l

3.64 ± 0.83

3.66 ± 0.87

3.75 ± 0.86

3.63 ± 0.87

HDL cholesterol, mmol/l

1.57 ± 0.43

1.58 ± 0.42

1.52 ± 0.42

1.46 ± 0.40a

Triglycerides, mmol/l

1.1 (0.8 to 1.4)

1.0 (0.7 to 1.3)

1.1 (0.7 to 1.5)

1.1 (0.8 to 1.5)

UACR, mg/mmol

0.23 (0.1 to 0.56)

0.23 (0.1 to 0.52)

0.19 (0.1 to 0.50)

0.28 (0.1 to 0.60)

UACR > =3.4 mg/mmol, n (%)

8 (2.0)

6 (1.5)

6 (1.5)

4 (1.0)

HbA1c %

5.53 ± 0.36

5.54 ± 0.34

5.56 ± 0.34

5.59 ± 0.40

Systolic BP, mmHg

129.3 ± 13.6

129.2 ± 13.6

129.9 ± 12.5

132.3 ± 12.8b

Diastolic BP, mmHg

80.9 ± 9.1

81.9 ± 9.0

82.2 ± 8.4

83.4 ± 8.1a

Pulse pressure, mmHg

74.6 ± 9.5

73.2 ± 10.2

74.3 ± 9.9

75.4 ± 10.1b

Antihypertensive medication, n (%)

 Diuretics

46 (11.3)

36 (8.8)

36 (8.8)

29 (7.1)b

 Beta blockers

23 (5.7)

17 (4.2)

19 (4.7)

13 (3.2)

 Calcium blockers

29 (7.1)

15 (3.7)

22 (5.4)

16 (3.9)

 Angiotensin-converting enzyme inhibitor

8 (2.0)

10 (2.5)

2 (0.5)

9 (2.2)

 Angiotensin II blockers

38 (9.3)

37 (9.1)

37 (9.1)

27 (6.7)

 Other

0

0

0

2 (0.5)

Educationc, n (%)

 Level 1

95 (23.3)

98 (24.2)

106 (26.1)

108 (26.9)

 Level 2

114 (28.0)

115 (28.1)

123 (30.3)

139 (34.7)

 Level 3

30 (7.3)

28 (6.9)

26 (6.4)

31 (7.7)

 Level 4

87 (22.4)

66 (17.1)

87 (22.5)

69 (18.1)

 Level 5

81 (20.0)

98 (24.2)

64 (15.8)

54 (13.5)

  1. Values are presented as n (%), means ± SD, or medians (interquartile ranges). Abbreviations: RENIS-T6 Renal Iohexol Clearance Survey in Tromsø 6, mGFR measured glomerular filtration rate, HDL high density lipoproteins, LDL low density lipoprotein, BP blood pressure, UACR urinary albumin creatinine ratio.
  2. ap < 0.001 for linear trends across quartiles
  3. bp < 0.05 for linear trend across quartiles
  4. cEducation level 1 indicated primary/secondary school, modern school, or technical school; level 2 indicated vocational school or 1–2 years senior high school; level 3 indicated a high school diploma; level 4 indicated college/university for less than 4 years; and level 5 indicated college/university for 4 years or more