Table 2 Influence of the three most common preoperative immunosuppressive medications on risk of renal failure and mortality
Immunosuppressant | n | Dialysis-dependent Renal failure, n (%) | p | Acute renal Failure, n (%) | p | Permanent Renal failure, n (%) | p | Mortality | p |
|---|---|---|---|---|---|---|---|---|---|
Tacrolimus | |||||||||
no | 46 | 9 (20%) | 0.009 | 12 (27%) | 0.041 | 10 (22%) | 0.032 | 14 (31%) | 0.012 |
yes | 55 | 2 (4%) | 6 (11%) | 4 (7%) | 6 (11%) | ||||
only | 10 | 2 (20%) | 0.002 | 3 (30%) | 0.034 | 3 (30%) | 0.002 | 4 (40%) | 0.001 |
combined with MMF | 45 | 0 (0%) | 3 (7%) | 1 (2%) | 2 (4%) | ||||
Cyclosporine | |||||||||
no | 69 | 4 (6%) | 0.06 | 8 (12%) | 0.016 | 6 (8%) | 0.027 | 11 (16%) | 0.153 |
yes | 32 | 7 (22%) | 10 (31%) | 8 (25%) | 9 (28%) | ||||
only | 16 | 3 (18%) | 0.780 | 5 (31%) | 1.000 | 3 (19%) | 0.564 | 4 (25%) | 0.780 |
combined with MMF | 16 | 4 (25%) | 5 (31%) | 5 (31%) | 5 (31%) | ||||
Mycophenolat mofetil | |||||||||
no | 34 | 6 (18%) | 0.121 | 9 (27%) | 0.106 | 7 (21%) | 0.163 | 10 (29%) | 0.084 |
yes | 67 | 5 (8%) | 9 (13%) | 7 (10%) | 10 (15%) | ||||
…and Tacrolimus | 45 | 0 (0%) | 0.001 | 3 (7%) | 0.015 | 1 (2%) | 0.001 | 2 (4%) | 0.001 |
…and Cyclosporin | 16 | 4 (25%) | 5 (31%) | 5 (31%) | 5 (31%) | ||||