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Table 2 Influence of the three most common preoperative immunosuppressive medications on risk of renal failure and mortality

From: The impact of immunosuppression on postoperative graft function after graft-unrelated surgery: a retrospective controlled cohort study

Immunosuppressant n Dialysis-dependent Renal failure, n (%) p Acute renal Failure, n (%) p Permanent Renal failure, n (%) p Mortality p
Tacrolimus
 no 46 9 (20%) 0.009 12 (27%) 0.041 10 (22%) 0.032 14 (31%) 0.012
 yes 55 2 (4%) 6 (11%) 4 (7%) 6 (11%)
 only 10 2 (20%) 0.002 3 (30%) 0.034 3 (30%) 0.002 4 (40%) 0.001
 combined with MMF 45 0 (0%) 3 (7%) 1 (2%) 2 (4%)
Cyclosporine
 no 69 4 (6%) 0.06 8 (12%) 0.016 6 (8%) 0.027 11 (16%) 0.153
 yes 32 7 (22%) 10 (31%) 8 (25%) 9 (28%)
 only 16 3 (18%) 0.780 5 (31%) 1.000 3 (19%) 0.564 4 (25%) 0.780
 combined with MMF 16 4 (25%) 5 (31%) 5 (31%) 5 (31%)
Mycophenolat mofetil
 no 34 6 (18%) 0.121 9 (27%) 0.106 7 (21%) 0.163 10 (29%) 0.084
 yes 67 5 (8%) 9 (13%) 7 (10%) 10 (15%)
 …and Tacrolimus 45 0 (0%) 0.001 3 (7%) 0.015 1 (2%) 0.001 2 (4%) 0.001
 …and Cyclosporin 16 4 (25%) 5 (31%) 5 (31%) 5 (31%)
  1. Bold entries are significant