Table 3 Univariate and multivariate Cox analysis of the factors associated with overall and cardiovascular mortality

Variable

HR (IC 95%)

p

HR (IC 95%)

p

HR (IC 95%)

p

HR (IC 95%)

p

Age

1.03 (1.00–1.05)

0.034

1.03 (1.01–1.05)

0.02

1.02 (0.98–1.07)

0.24

–

Male

1.23 (0.72–2.10)

0.45

–

1.19 (0.57–2.50)

0.65

–

Haemodialysis

1.2 (0.71–2.03)

0.5

–

1.49 (0.64–3.44)

0.35

–

Haemodialysis vintage

1.0 (0.99–1.00)

0.95

–

1 (0.99–1.00)

0.38

–

Hypertension

1.43 (0.71–2.88)

0.31

–

2.16 (0.61–7.60)

0.23

–

Diabetes Mellitus

1.12 (0.63–2.00)

0.69

–

0.84 (0.34–2.09)

0.71

–

Smoker

1.18 (0.57–2.43)

0.66

–

3.19 (0.91–11.2)

0.07

–

History of stroke event

0.63 (0.32–1.24)

0.18

–

0.31 (0.11–0.87)

0.03

0.56 (0.16–1.94)

0.36

History of cardiologic event

1.63 (0.92–2.88)

0.09

1.81 (1.09–3.03)

0.02

1.3 (0.6–2.82)

0.51

–

Chronic ischemic heart disease

1.82 (0.97–3.41)

0.06

1.58 (0.67–3.72)

0.30

–

Antiplatelet treatment

1.15 (0.67–1.96)

0.62

–

0.91 (0.44–1.88)

0.80

–

Statin treatment

1.43 (0.83–2.47)

0.20

–

1.36 (0.65–2.83)

0.42

–

Vit. D treatment

1.23 (0.72–2.09)

0.44

–

1.36 (0.65–2.84)

0.41

–

Calcium salt use

1.01 (0.59–1.74)

0.98

–

1.86 (0.86–4.01)

0.12

–

Phosphate binder use

0.64 (0.37–1.13)

0.13

–

1.87 (0.88–4.01)

0.11

–

Cinacalcet treatment

0.62 (0.26–1.47)

0.28

–

0.41 (0.12–1.41)

0.16

–

Cholesterol

1.00 (0.99–1.00)

0.59

–

1.00 (0.99–1.01)

0.77

–

LDL-cholesterol

0.99 (0.99–1.00)

0.20

–

1.00 (0.99–1.01)

0.65

–

HDL-cholesterol

1.01 (0.99–1.01)

0.50

–

1.00 (0.99–1.00)

0.82

–

Triglycerides

0.99 (0.995–1)

0.02

1.00 (0.73–1.30)

0.08

Uric acid

0.95 (0.82–1.11)

0.50

–

0.97 (0.73–1.30)

0.83

–

HbA1c

1.21 (0.94–1.53)

0.14

–

1.21 (0.83–1.77)

0.32

–

Albumin

1.06 (0.58–1.93)

0.86

–

0.40 (0.12–1.35)

0.14

–

Creatinine

0.99 (0.93–1.05)

0.64

–

0.92 (0.84–1.01)

0.08

–

Urea

1.00 (0.99–1.01)

0.32

–

1.00 (0.99–1.00)

0.24

–

Phosphorous

0.90 (0.76–1.06)

0.19

–

1.06 (0.79–1.41)

0.72

–

Calcium

0.93 (0.68–1.30)

0.68

–

0.39 (0.19–0.84)

0.02

0.37 (0.18–0.78)

0.01

Ca X P product

0.99 (0.97–1.00)

0.16

–

1.00 (0.12–1.35)

0.14

–

Bicarbonate

1.03 (0.97–1.09)

0.4

–

1.11 (1–1.23)

0.06

Intact PTH

1.00 (0.99–1.00)

0.94

–

1.00 (0.99–1.00)

0.30

–

TSH

1.07 (1.01–1.14)

0.03

1.05 (0.98–1.12)

0.15

–

CRP

1.00 (0.99–1.007)

0.76

–

1.02 (0.98–1.07)

0.26

–

CaCs ≥400 HU

2.15 (0.95–4.84)

0.07

1.55 (0.84–2.87)

0.16

5.91 (1.18–29.48)

0.03

5.01 (1.28–19.59)

0.02