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Table 3 Univariate and multivariate Cox analysis of the factors associated with overall and cardiovascular mortality

From: Coronary calcification as a predictor of cardiovascular mortality in advanced chronic kidney disease: a prospective long-term follow-up study

  Overall mortality Cardiovascular mortality
Univariate Cox Multivariate Cox Univariate Cox Multivariate Cox
Variable HR (IC 95%) p HR (IC 95%) p HR (IC 95%) p HR (IC 95%) p
Age 1.03 (1.00–1.05) 0.034 1.03 (1.01–1.05) 0.02 1.02 (0.98–1.07) 0.24  
Male 1.23 (0.72–2.10) 0.45   1.19 (0.57–2.50) 0.65  
Haemodialysis 1.2 (0.71–2.03) 0.5   1.49 (0.64–3.44) 0.35  
Haemodialysis vintage 1.0 (0.99–1.00) 0.95   1 (0.99–1.00) 0.38  
Hypertension 1.43 (0.71–2.88) 0.31   2.16 (0.61–7.60) 0.23  
Diabetes Mellitus 1.12 (0.63–2.00) 0.69   0.84 (0.34–2.09) 0.71  
Smoker 1.18 (0.57–2.43) 0.66   3.19 (0.91–11.2) 0.07  
History of stroke event 0.63 (0.32–1.24) 0.18   0.31 (0.11–0.87) 0.03 0.56 (0.16–1.94) 0.36
History of cardiologic event 1.63 (0.92–2.88) 0.09 1.81 (1.09–3.03) 0.02 1.3 (0.6–2.82) 0.51  
Chronic ischemic heart disease 1.82 (0.97–3.41) 0.06    1.58 (0.67–3.72) 0.30  
Antiplatelet treatment 1.15 (0.67–1.96) 0.62   0.91 (0.44–1.88) 0.80  
Statin treatment 1.43 (0.83–2.47) 0.20   1.36 (0.65–2.83) 0.42  
Vit. D treatment 1.23 (0.72–2.09) 0.44   1.36 (0.65–2.84) 0.41  
Calcium salt use 1.01 (0.59–1.74) 0.98   1.86 (0.86–4.01) 0.12  
Phosphate binder use 0.64 (0.37–1.13) 0.13   1.87 (0.88–4.01) 0.11  
Cinacalcet treatment 0.62 (0.26–1.47) 0.28   0.41 (0.12–1.41) 0.16  
Cholesterol 1.00 (0.99–1.00) 0.59   1.00 (0.99–1.01) 0.77  
LDL-cholesterol 0.99 (0.99–1.00) 0.20   1.00 (0.99–1.01) 0.65  
HDL-cholesterol 1.01 (0.99–1.01) 0.50   1.00 (0.99–1.00) 0.82  
Triglycerides 0.99 (0.995–1) 0.02    1.00 (0.73–1.30) 0.08   
Uric acid 0.95 (0.82–1.11) 0.50   0.97 (0.73–1.30) 0.83  
HbA1c 1.21 (0.94–1.53) 0.14   1.21 (0.83–1.77) 0.32  
Albumin 1.06 (0.58–1.93) 0.86   0.40 (0.12–1.35) 0.14  
Creatinine 0.99 (0.93–1.05) 0.64   0.92 (0.84–1.01) 0.08  
Urea 1.00 (0.99–1.01) 0.32   1.00 (0.99–1.00) 0.24  
Phosphorous 0.90 (0.76–1.06) 0.19   1.06 (0.79–1.41) 0.72  
Calcium 0.93 (0.68–1.30) 0.68   0.39 (0.19–0.84) 0.02 0.37 (0.18–0.78) 0.01
Ca X P product 0.99 (0.97–1.00) 0.16   1.00 (0.12–1.35) 0.14  
Bicarbonate 1.03 (0.97–1.09) 0.4   1.11 (1–1.23) 0.06   
Intact PTH 1.00 (0.99–1.00) 0.94   1.00 (0.99–1.00) 0.30  
TSH 1.07 (1.01–1.14) 0.03    1.05 (0.98–1.12) 0.15  
CRP 1.00 (0.99–1.007) 0.76   1.02 (0.98–1.07) 0.26  
CaCs ≥400 HU 2.15 (0.95–4.84) 0.07 1.55 (0.84–2.87) 0.16 5.91 (1.18–29.48) 0.03 5.01 (1.28–19.59) 0.02