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Table 2 Pathways for the “biosynthesis of cell constituents”

From: Transcriptome analysis of signaling pathways of human peritoneal mesothelial cells in response to different osmotic agents in a peritoneal dialysis solution

Signaling pathways

HPG (d3)

PYS (d3)

PYS (d7)

Diphthamide biosynthesis

DPH6

  

Dermatan, chondroitin or heparan sulfate biosynthesis

CHST1

XYLT2, CSGALNACT2, HS3ST1, DSEL

CHST1

S-adenosyl-L-methionine or cysteine biosynthesis III (mammalian)

MAT2A

MAT2A, EHMT1, NSUN4

 

Leukotriene biosynthesis

 

MGST3

MGST3

Chondroitin or dermatan biosynthesis

 

CSGALNACT2

 

Glycoaminoglycan-protein linkage region biosynthesis

 

XYLT2

 

Inositol pyrophosphate biosynthesis

 

IPMK, IP6K2

 

D-myo-inositol (1,3,4, 5)-trisphosphate or 1D-myo-inositol hexakisphosphate biosynthesis II

 

IPMK, ITPKB, PLCZ1

 

D-myo-inositol (1,3,4, 5, 6)-tetrakisphosphate or 3-phosphoinositide biosynthesis

 

IPMK, PPP1R16B, DUSP1, PPP1R8, DUSP10, PPTC7, DUSP12, FGFR1, RNGTT, PTPRF

 

Citrulline biosynthesis

 

GLS, ARG2

 

Lipoate biosynthesis and incorporation II

 

LIPT1

 

Spermine or spermidine biosynthesis

 

AMD1

 

Uridine-5′-phosphate biosynthesis or pyrimidine ribonucleotides de novo biosynthesis

 

UMPS, BLM

 

Fatty acid biosynthesis initiation II

 

OXSM

 

Serine, glycine or dTMP de novo biosynthesis

 

SHMT1

 

Aspartate biosynthesis

 

GOT1

 

CMP-N-acetylneuraminate biosynthesis I (eukaryotes)

 

GNE

 

Ceramide biosynthesis

 

KDSR

 

CDP-diacylglycerol biosynthesis 1, phosphatidylglycerol biosynthesis II (Non-plastidic) or triacylglycerol biosynthesis

 

TAMM41, AGPAT5

 

Phosphatidylethanolamine biosynthesis II

 

ETNK1

 

Dolichyl-diphosphooligosaccharide biosynthesis

 

ALG13

 

Estrogen biosynthesis

 

CYP1A1, HSD17B2

 

Stearate biosynthesis I (Animals)

 

ZADH2

 
  1. Three separate RNA samples were included in each group (n = 3). The upregulated transcripts were highlighted in bold. Others were downregulated