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Table 4 Pathways for the “interactions with leukocytes”

From: Transcriptome analysis of signaling pathways of human peritoneal mesothelial cells in response to different osmotic agents in a peritoneal dialysis solution

Signaling pathways HPG (d3) PYS (d3) PYS (d7)
IL-22 signaling IL22RA2   
Th1 and Th2 Pathways or T helper cell differentiation TNFSF4 NOTCH2, NFIL3, IL4R, PSENEN, HLA-DMA, HLA-A, IL1RL1, FGFR1, MAF, HLA-DMB, CD274, MAK, BCL6 HLA-DMB
LPS/IL-1 mediated inhibition of RXR function CHST1 IL1RL1, ABCC2, CPT2, HS3ST1, GSTO2, MGST3, ABCA1 CHST1, SREBF1, MGST3
IL-4, Nur77 signaling in T lymphocytes, or antigen presentation   HLA-DMA, HLA-A, HLA-DMB, IL4R, FGFR1 HLA-DMB, TAPBP
Leukocyte extravasation signaling   BTK, CLDN10, CLDN4, FGFR1, CD44, MMP12, BCAR1, CTNND1, PRKCA MMP12
IL-6, IL-10, IL-17A, CD40 or TNFR1/2 signaling   COL1A1, CSNK2A2, FOS, TRAF5, FGFR1, IL4R, IL1RL1, ARG2, NAIP, MAP3K14
IL-1 or IL-8 signaling   GNB4, FOS, GNAQ, RND3, FLT1, FGFR1, HBEGF, PRKCA MAP3K14, GNAS
GM-CSF, IL-2, IL-3, IL-7, IGF-1 or TGF-beta signaling   RUNX1, CSNK2A2, FOS, FGFR1, PRKCA, CDKN1B, YWHAE, BCL6, BMP4, SERPINE1  
IL-12 signaling or production in macrophages   FOS, ALB, ORM1, FGFR1, MAF, PRKCA  
Natural killer cell signaling   FGFR1, SH3BP2, KIR3DL3, PRKCA  
Cytotoxic T lymphocyte-mediated apoptosis of target cells, or granzyme B signaling   HLA-A, DFFB  
Antiproliferative role of TOB in T cell signaling   TOB1, CDKN1B  
  1. Three separate RNA samples were included in each group (n = 3). The upregulated transcripts were highlighted in bold. Others were downregulated