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Table 4 AUCs for AKI stratified according to admission serum glucose concentrations

From: Impact of blood glucose levels on the accuracy of urinary N-acety-β-D-glucosaminidase for acute kidney injury detection in critically ill adults: a multicenter, prospective, observational study

Glucose (mg/dl) AKI (n, %) AUC-ROC 95% CI Cut-off (U/g Cr) Sensitivity Specificity
Total AKI (n = 412)
 <110 (n = 448) 77 (17.2) 0.643 ± 0.034 0.597–0.687 21.04 0.727 0.496
 110 to < 140 (n = 468) 119 (25.4) 0.645 ± 0.029 0.600–0.689 28.47 0.546 0.673
 140 to < 170 (n = 275) 93 (33.8) 0.639 ± 0.036 0.579–0.696 32.89 0.613 0.654
 170 to < 200 (n = 123) 51 (41.5) 0.634 ± 0.052 0.543–0.719 29.80 0.726 0.569
  ≥ 200 (n = 123) 72 (58.5) 0.651 ± 0.052 0.560–0.735 28.03 0.778 0.549
Severe AKI (n = 109)
 <110 (n = 448) 18 (4.0) 0.703 ± 0.068 0.658–0.745 38.37 0.667 0.770
 110 to < 140 (n = 468) 27 (5.8) 0.756 ± 0.048 0.714–0.794 31.65 0.778 0.687
 140 to < 170 (n = 275) 28 (10.2) 0.679 ± 0.049 0.621–0.734 33.95 0.750 0.615
 170 to < 200 (n = 123) 13 (10.6) 0.680 ± 0.086 0.590–0.762 49.25 0.616 0.736
 ≥200 (n = 123) 23 (18.7) 0.703 ± 0.054 0.614–0.782 35.01 0.870 0.560
  1. AUC area under the receiver operating characteristic curve, AKI acute kidney injury, n sample size, 95% CI, 95% confidence interval
  2. Total AKI:
  3. < 110 mg/dl versus 110 to < 140 mg/dl Z = 0.045, P = 0.964
  4. < 110 mg/dl versus 140 to < 170 mg/dl Z = 0.081, P = 0.935
  5. < 110 mg/dl versus 170 to < 200 mg/dl Z = 0.145, P = 0.885
  6. < 110 mg/dl versus ≥200 mg/dl Z = 0.129, P = 0.897
  7. 110 to < 140 mg/dl versus 140 to < 170 mg/dl Z = 0.131, P = 0.895
  8. 110 to < 140 mg/dl versus 170 to < 200 mg/dl Z = 0.185, P = 0.853
  9. 110 to < 140 mg/dl versus ≥200 mg/dl Z = 0.102, P = 0.919
  10. 140 to < 170 mg/dl versus 170 to < 200 mg/dl Z = 0.079, P = 0.937
  11. 140 to < 170 mg/dl versus ≥200 mg/dl Z = 0.192, P = 0.848
  12. 170 to < 200 mg/dl versus ≥200 mg/dl Z = 0.232, P = 0.816
  13. Severe AKI:
  14. < 110 mg/dl versus 110 to < 140 mg/dl Z = 0.635, P = 0.525
  15. < 110 mg/dl versus 140 to < 170 mg/dl Z = 0.287, P = 0.774
  16. < 110 mg/dl versus 170 to < 200 mg/dl Z = 0.210, P = 0.834
  17. < 110 mg/dl versus ≥200 mg/dl Z = 0, P = 1
  18. 110 to < 140 mg/dl versus 140 to < 170 mg/dl Z = 1.125, P = 0.261
  19. 110 to < 140 mg/dl versus 170 to < 200 mg/dl Z = 0.773, P = 0.440
  20. 110 to < 140 mg/dl versus ≥200 mg/dl Z = 0.734, P = 0.463
  21. 140 to < 170 mg/dl versus 170 to < 200 mg/dl Z = 0.010, P = 0.992
  22. 140 to < 170 mg/dl versus ≥200 mg/dl Z = 0.331, P = 0.740
  23. 170 to < 200 mg/dl versus ≥200 mg/dl Z = 0.227, P = 0.820