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Table 1 Baseline Clinical and Demographic Characteristics in Patients With and Without CI-AKI

From: Negative association between free triiodothyronine level and contrast-induced acute kidney injury in patients undergoing primary percutaneous coronary intervention

Variables Total CI-AKI(−) CI-AKI(+) P-value
(n = 363) (n = 304) (n = 59)
Demographics
 Age, years 64.07 ± 12.52 63.39 ± 12.29 67.58 ± 13.18 0.019
 Age > 75 years, n (%) 72 (19.8%) 52 (17.1%) 20 (33.9%) 0.003
 Sex, female, n (%) 56 (15.4%) 47 (15.5%) 9 (15.3%) 0.968
Medical history
 Smoker 207 (57.0%) 173 (56.9%) 34 (57.6%) 0.919
 Prior PCI, n (%) 9 (2.5%) 7 (2.3%) 2 (3.4%) 0.644
 Prior myocardial infarction, n (%) 7 (1.9%) 5 (1.6%) 2 (3.4%) 0.318
 Hypertension, n (%) 218 (60.1%) 181 (59.5%) 37 (62.7%) 0.649
 Diabetes, n (%) 99 (27.3%) 79 (26.0%) 20 (33.9%) 0.212
 Anemia, n (%) 103 (28.6%) 85 (28.2%) 18 (30.5%) 0.724
Laboratory measurements
 fT3, pmol/L 3.67 ± 0.86 3.74 ± 0.83 3.33 ± 0.94 0.001
 fT4, pmol/L 16.06 ± 3.70 15.91 ± 3.81 16.82 ± 2.95 0.085
 TSH, mIU/L 0.77 (0.49–1.31) 0.77 (0.50–1.26) 0.79 (0.48–1.59) 0.770
 Low fT3, n (%) 80 (22.0%) 55 (18.1%) 25 (42.4%) <0.0001
 Serum creatinine, mg/dl 0.81 (0.69–0.97) 0.80 (0.68–0.95) 0.86 (0.75–0.86) 0.027
 Serum creatinine>1.5 mg/dl, n (%) 15 (3.9%) 6 (2.0%) 9 (15.3%) <0.0001
 eGFR, mL/min per 1.73 m2(MDRD) 98.23 (81.09–118.69) 99.65 (82.35–119.51) 89.17 (67.62–110.62) 0.014
 eGFR< 60 mL/min per 1.73 m2(MDRD) 29 (8.0%) 18 (5.9%) 11 (18.6%) 0.001
 eGFR, mL/min per 1.73 m2(CKD-EPI) 91.21 (78.25–101.78) 93.78 (79.57–102.11) 84.83 (61.67–94.93) 0.002
 eGFR< 60 mL/min per 1.73 m2(CKD-EPI) 34 (9.4%) 21 (6.9%) 13 (22.0%) <0.0001
 Hemoglobin, g/l 139.30 ± 17.33 139.83 ± 16.12 136.59 ± 22.47 0.190
 Hematocrit 0.41 ± 0.05 0.41 ± 0.04 0.4 ± 0.06 0.691
 Cholesterol, mmol/l 4.84 ± 1.21 4.88 ± 1.20 4.63 ± 1.24 0.149
 Triglyceride, mmol/l 1.25 (0.90–1.70) 1.28 (0.91–1.72) 1.14 (0.85–1.55) 0.08
 LVEF,% 52.82 ± 8.38 53.83 ± 7.67 47.04 ± 9.90 <0.0001
 LVEF < 0.45, n (%) 66 (18.2%) 44 (14.5%) 22 (37.3%) <0.0001
Medication, n (%)
 Antiplatelet, n (%) 355 (97.8%) 298 (98.0%) 57 (96.6%) 0.501
 Statin, n (%) 362 (99.7%) 303 (99.7%) 59 (100.0%) 0.659
 Diuretic, n (%) 205 (56.5%) 158 (52.0%) 47 (79.7%) <0.0001
Procedure performed
 Number of diseased vessels, n 1.93 ± 1.08 1.88 ± 1.10 2.19 ± 0.92 0.481
 Stent length 33 (23–51) 28 (23–51) 33 (23–47) 0.305
 Perioperative hypotension, n (%) 130 (35.8%) 95 (31.2%) 35 (59.3%) <0.0001
 IABP, n (%) 12 (3.3%) 5 (1.6%) 7 (11.9%) <0.0001
 Contrast volume > 200 ml, n (% 270 (74.4%) 219 (72.0%) 51 (86.4%) 0.020
  1. Abbreviations:CI-AKI contrast-induced acute kidney injury, PCI percutaneous coronary intervention, fT3 free triiodothyronine, fT4 free thyroxine, TSH thyroid stimulating hormone, eGFR estimated glomerular filtration rate, LVEF left ventricular ejection fraction, IABP intra-aortic balloon pump