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Table 1 Baseline Clinical and Demographic Characteristics in Patients With and Without CI-AKI

From: Negative association between free triiodothyronine level and contrast-induced acute kidney injury in patients undergoing primary percutaneous coronary intervention

Variables

Total

CI-AKI(−)

CI-AKI(+)

P-value

(n = 363)

(n = 304)

(n = 59)

Demographics

 Age, years

64.07 ± 12.52

63.39 ± 12.29

67.58 ± 13.18

0.019

 Age > 75 years, n (%)

72 (19.8%)

52 (17.1%)

20 (33.9%)

0.003

 Sex, female, n (%)

56 (15.4%)

47 (15.5%)

9 (15.3%)

0.968

Medical history

 Smoker

207 (57.0%)

173 (56.9%)

34 (57.6%)

0.919

 Prior PCI, n (%)

9 (2.5%)

7 (2.3%)

2 (3.4%)

0.644

 Prior myocardial infarction, n (%)

7 (1.9%)

5 (1.6%)

2 (3.4%)

0.318

 Hypertension, n (%)

218 (60.1%)

181 (59.5%)

37 (62.7%)

0.649

 Diabetes, n (%)

99 (27.3%)

79 (26.0%)

20 (33.9%)

0.212

 Anemia, n (%)

103 (28.6%)

85 (28.2%)

18 (30.5%)

0.724

Laboratory measurements

 fT3, pmol/L

3.67 ± 0.86

3.74 ± 0.83

3.33 ± 0.94

0.001

 fT4, pmol/L

16.06 ± 3.70

15.91 ± 3.81

16.82 ± 2.95

0.085

 TSH, mIU/L

0.77 (0.49–1.31)

0.77 (0.50–1.26)

0.79 (0.48–1.59)

0.770

 Low fT3, n (%)

80 (22.0%)

55 (18.1%)

25 (42.4%)

<0.0001

 Serum creatinine, mg/dl

0.81 (0.69–0.97)

0.80 (0.68–0.95)

0.86 (0.75–0.86)

0.027

 Serum creatinine>1.5 mg/dl, n (%)

15 (3.9%)

6 (2.0%)

9 (15.3%)

<0.0001

 eGFR, mL/min per 1.73 m2(MDRD)

98.23 (81.09–118.69)

99.65 (82.35–119.51)

89.17 (67.62–110.62)

0.014

 eGFR< 60 mL/min per 1.73 m2(MDRD)

29 (8.0%)

18 (5.9%)

11 (18.6%)

0.001

 eGFR, mL/min per 1.73 m2(CKD-EPI)

91.21 (78.25–101.78)

93.78 (79.57–102.11)

84.83 (61.67–94.93)

0.002

 eGFR< 60 mL/min per 1.73 m2(CKD-EPI)

34 (9.4%)

21 (6.9%)

13 (22.0%)

<0.0001

 Hemoglobin, g/l

139.30 ± 17.33

139.83 ± 16.12

136.59 ± 22.47

0.190

 Hematocrit

0.41 ± 0.05

0.41 ± 0.04

0.4 ± 0.06

0.691

 Cholesterol, mmol/l

4.84 ± 1.21

4.88 ± 1.20

4.63 ± 1.24

0.149

 Triglyceride, mmol/l

1.25 (0.90–1.70)

1.28 (0.91–1.72)

1.14 (0.85–1.55)

0.08

 LVEF,%

52.82 ± 8.38

53.83 ± 7.67

47.04 ± 9.90

<0.0001

 LVEF < 0.45, n (%)

66 (18.2%)

44 (14.5%)

22 (37.3%)

<0.0001

Medication, n (%)

 Antiplatelet, n (%)

355 (97.8%)

298 (98.0%)

57 (96.6%)

0.501

 Statin, n (%)

362 (99.7%)

303 (99.7%)

59 (100.0%)

0.659

 Diuretic, n (%)

205 (56.5%)

158 (52.0%)

47 (79.7%)

<0.0001

Procedure performed

 Number of diseased vessels, n

1.93 ± 1.08

1.88 ± 1.10

2.19 ± 0.92

0.481

 Stent length

33 (23–51)

28 (23–51)

33 (23–47)

0.305

 Perioperative hypotension, n (%)

130 (35.8%)

95 (31.2%)

35 (59.3%)

<0.0001

 IABP, n (%)

12 (3.3%)

5 (1.6%)

7 (11.9%)

<0.0001

 Contrast volume > 200 ml, n (%

270 (74.4%)

219 (72.0%)

51 (86.4%)

0.020

  1. Abbreviations:CI-AKI contrast-induced acute kidney injury, PCI percutaneous coronary intervention, fT3 free triiodothyronine, fT4 free thyroxine, TSH thyroid stimulating hormone, eGFR estimated glomerular filtration rate, LVEF left ventricular ejection fraction, IABP intra-aortic balloon pump