Table 3 Laboratory data at admission of patients with methanol intoxication, stratified according to status of renal damage as AKI or non-AKI (N = 50)
From: Acute kidney injury and the risk of mortality in patients with methanol intoxication
Variable | AKI patients (n = 33) | Non-AKI patients (n = 17) | All patients (N = 50) | P value |
|---|---|---|---|---|
Blood urea nitrogen, mg/dL | 22.4 ± 18.1 | 12.4 ± 4.3 | 18.8 ± 15.4 | 0.035* |
Creatinine, mg/dL (admission) | 2.51 ± 1.24 | 0.87 ± 0.17 | 1.97 ± 1.28 | 0.000*** |
Creatinine, mg/dL (peak) | 3.23 ± 2.00 | 1.12 ± 0.94 | 2.54 ± 1.99 | 0.000*** |
Methanol level, mg/dL | 33.1 ± 77.2 | 64.5 ± 75.5 | 43.8 ± 77.4 | 0.176 |
Ethanol level, mg/dL | 48.6 ± 57.0 | 71.6 ± 125.3 | 56.4 ± 85.8 | 0.390 |
Arterial blood gas | Â | Â | Â | Â |
pH | 7.055 ± 0.232 | 7.306 ± 0.190 | 7.141 ± 0.248 | 0.000*** |
pCO2, mmHg | 26.5 ± 14.1 | 36.9 ± 11.1 | 30.0 ± 13.9 | 0.011* |
pO2, mmHg | 110.3 ± 60.0 | 112.8 ± 58.7 | 111.2 ± 59.0 | 0.890 |
Bicarbonate, mmol/L | 8.7 ± 7.3 | 18.8 ± 6.8 | 12.2 ± 8.6 | 0.000*** |
Base excess, mmol/L | −17.9 ± 10.0 | −7.4 ± 9.1 | −13.5 ± 10.9 | 0.001** |
Osmolarity, mOsm/kg H2O | 341.0 ± 42.1 | 329.3 ± 26.0 | 336.9 ± 37.4 | 0.351 |
Osmolarity gap, mOsm/kg H2O | 50.5 ± 84.2 | 37.3 ± 28.4 | 44.7 ± 65.0 | 0.624 |
Anion gap, mmol/L | 33.4 ± 14.8 | 16.3 ± 7.3 | 27.2 ± 15.0 | 0.000*** |
Calcium, mEq/L | 7.7 ± 0.9 | 7.5 ± 0.9 | 7.7 ± 0.9 | 0.526 |
Sodium, mEq/L | 138.1 ± 6.1 | 141.7 ± 3.1 | 139.3 ± 5.5 | 0.029* |
Potassium, mEq/L | 4.6 ± 1.1 | 3.5 ± 0.6 | 4.2 ± 1.1 | 0.001* |
Chloride, mEq/L | 96.8 ± 8.9 | 106.9 ± 3.5 | 100.6 ± 8.8 | 0.000*** |
Amylase, mg/dL | 137.8 ± 84.0 | 294.3 ± 477.4 | 182.5 ± 250.7 | 0.310 |
Lipase, mg/dL | 179.1 ± 206.4 | 39.5 ± 14.0 | 154.8 ± 194.4 | 0.199 |
Albumin, g/dL | 3.05 ± 1.01 | 3.57 ± 0.69 | 3.26 ± 0.91 | 0.297 |
Aspartate aminotransferase, U/L | 303.7 ± 507.1 | 50.3 ± 37.9 | 245.2 ± 455.6 | 0.240 |
Alanine aminotransferase, U/L | 96.4 ± 122.1 | 32.0 ± 24.7 | 73.9 ± 103.6 | 0.060 |
Random glucose, mg/dL | 223.6 ± 145.5 | 126.6 ± 34.1 | 183.0 ± 121.8 | 0.026* |
White blood cell count, 1000/μL | 16.2 ± 9.7 | 11.6 ± 6.1 | 14.6 ± 8.8 | 0.077 |
Haemoglobin, g/dL | 13.2 ± 3.1 | 14.0 ± 1.6 | 13.5 ± 2.7 | 0.311 |
Platelet count, 1000/μL | 192.2 ± 109.6 | 242.9 ± 68.4 | 209.4 ± 99.8 | 0.089 |