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Table 3 Factors associated with echocardiographic measurements at follow up based on multivariate analysis

From: Cardiac structure and function after revascularization versus medical therapy for renal artery stenosis: the ASTRAL heart echocardiographic sub-study

Measurement Significant factors Estimate Standard Error 95% CI p
AoRD Baseline AoRD 0.83 0.08 0.66 to 0.99 < 0.0001
Beta-blocker use - No 0.20 0.07 0.07 to 0.34 0.004
LVOT velocity Baseline LVOT velocity 0.73 0.08 0.58 to 0.88 < 0.0001
LVEF Baseline LVEF 0.61 0.08 0.45 to 0.77 < 0.0001
LA diameter Baseline LA diameter 0.88 0.11 0.67 to 1.10 < 0.0001
LVESD Baseline LVESD 0.51 0.08 0.34 to 0.67 < 0.0001
LVEDD Baseline LVEDD 0.52 0.08 0.35 to 0.68 < 0.0001
Age −0.01 0.005 −0.02 to − 0.0003 0.04
LV mass Baseline LV mass 0.60 0.09 0.42 to 0.77 < 0.0001
Coronary heart disease - No 20.1 6.54 7.02 to 33.19 0.003
eGFR −0.49 0.20 −0.89 to − 0.09 0.02
ACE inhibitor use - No −13.2 6.26 −25.74 to −0.68 0.04
E:A Baseline E:A 0.38 0.11 0.15 to 0.61 0.002
Diabetes - No −0.30 0.14 − 0.58 to − 0.01 0.04
EDT Baseline EDT 0.40 0.10 0.20 to 0.59 0.0001
Age 1.99 0.95 0.08 to 3.89 0.04
eGFR 0.93 0.38 0.17 to 1.68 0.01
RWT Baseline RWT 0.68 0.08 0.51 to 0.84 < 0.001
Beta-Blocker use - No −0.02 0.01 −0.04 to −0.001 0.04
ACE inhibitor use - No −0.03 0.01 −0.06 to − 0.01 0.003
  1. Key: LVOT left ventricular outflow tract, LVEF left ventricular ejection fraction, LA left atrium, LVESD left ventricular end systolic diameter, LVEDD left ventricular end diastolic diameter, EDT E wave deceleration time, RWT relative wall thickness, CI confidence intervals, eGFR estimated glomerular filtration rate, AoRD aortic root diameter
  2. Each model included the following variables: treatment group, age, presence of diabetes, history of coronary heart disease, systolic blood pressure, diastolic blood pressure, degree of stenosis to most affected kidney, renal function using eGFR, prescription of beta-blockers and renin angiotensin blockade and the baseline ventricular measurement