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Table 1 Baseline characteristics among kidney transplant recipients from donors > 65 years and ≤ 65 years

From: Early outcomes of kidney transplantation from elderly donors after circulatory death (GEODAS study)

 

Donor ≤65 years

(n = 426)

Donor > 65 years

(n = 135)

p-value

Recipient characteristics

 Age (years, mean (SD))

53.7 (11.4)

65.8 (8.8)

< 0.001

  Age > 65 years (%)

14.6

61.3

< 0.001

 Female Gender (%)

30.1

35.6

0.23

 Black Race (%)

1.4

0.7

0.5

 Diabetes mellitus (%)

26.1

51.4

< 0.001

 Previous cardiovascular eventa (%)

7.8

20.7

< 0.001

Cause of end-stage renal disease (%)

Hypertensive nephropathy

12.4

11.9

 

Diabetic nephropathy

11.3

22.2

 

Glomerulonephritis

19.0

12.6

 

Interstitial

11.0

11.9

0.03

Polycystic

15.3

11.1

 

Others

6.7

5.9

 

Unknown

19.7

23.7

 

Previous renal replacement therapy (%)

Hemodialysis

73.1

83.0

 

Peritoneal Dialysis

21.0

14.8

0.05

Preemptive kidney transplant

5.9

2.2

 

 Dialysis vintage (years, median [IQR])

1.1 [2.0–3.6]

1.3 [2.6–4.0]

0.08

 Patients with previous kidney transplant (%)

8.4

7.4

0.7

 Donor characteristics

 Age (years, mean (SD))

52.7 (9.1)

72.0 (4.9)

< 0.001

 Female Gender (%)

26.3

45.9

< 0.001

 Expanded criteria donors (%)

29.3

100

< 0.001

 Stroke as Cause of death (%)

49.2

67.8

< 0.001

 Transplant characteristics

 Number of HLA mismatches (median (IQR))

4 [3–5]

4 [3–5]

0.003

 Cold ischemia time (hours, median (IQR))

11 [7–18]

9.5 [7–16.5]

0.326

 Warm ischemia time (min, median (IQR))

23.5 [15–36.5]

26 [16–35]

0.901

 Induction treatment (Thymoglobulin, %)

70.7

57

0.003

 Maintenance (Tacrolimus+MPA + steroids, %)

82.9

80.7

0.57

 Time of follow-up (years, median [IQR])

1.6 [0.9–2.6]

1.1 [0.7–1.8]

< 0.001

  1. SD standard deviation, MPA mycophenolic acid, IQR interquartile range
  2. aAcute myocardial infarction, stroke or peripheral vascular disease (amputation)