Early outcomes of kidney transplantation from elderly donors after circulatory death (GEODAS study)

BMC Nephrology

Table 4 Risk factors for relevant patient and allograft early outcomes estimated with Cox regression analysis (HR) and competing risk analysis (sHR)

	Risk factor	HR	95% CI	p-value	sHR	95% CI	p-value
Patient survival
Model 1 (raw)	Donor age > 65y (vs ≤ 65 years)	2.94	[1.22–7.11]	0.016	3.17	[1.38–7.27]	0.015
Model 2 (adjusted by recipient age)	Donor age > 65y (vs ≤ 65 years)	1.17	[0.44–3.08]	0.751	1.26	[0.48–3.34]	0.636
Model 2 (adjusted by recipient age)	Recipient age	1.10	[1.04–1.16]	0.001	1.1	[1.05–1.16]	< 0.001
Model 3 (adjusted by recipient age + previous CV event)	Donor age > 65y (vs ≤ 65 years)	1.06	[0.40–2.82]	0.900	1.06	[0.36–3.12]	0.910
	Recipient age	1.10	[1.04–1.16]	0.001	1.09	[1.04–1.15]	< 0.001
	Previous CV event	2.02	[0.76–5.36]	0.158	2.00	[0.73–5.47]	0.178
Death-censored graft survival
Model 1 (raw)	Donor age > 65y (vs ≤ 65 years)	1.30	[0.47–3.60]	0.620	1.28	[0.47–3.47]	0.631
Model 2 (adjusted by recipient age)	Donor age > 65y (vs ≤ 65 years)	1.17	[0.44–3.08]	0.751	1.00	[0.30–3.38]	0.997
Model 2 (adjusted by recipient age)	Recipient age	1.10	[1.04–1.16]	0.001	1.02	[0.97–1.07]	0.425
Model 3 (adjusted by eGFR< 30 ml/min at first month)	Donor age > 65y (vs ≤ 65 years)	0.66	0.15–3.01	0.595	0.58	[0.12–2.74]	0.487
Model 3 (adjusted by eGFR< 30 ml/min at first month)	eGFR< 30 ml/min at first month	8.70	2.99–25.25	< 0.001	8.34	2.82–24.65	< 0.001

HR hazard ratio, sHR sub-hazard ratio, CI confidence interval, eGFR estimated glomerular filtration rate, CV cardiovascular

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