Fig. 2

Male Slc3a1^−/− mice demonstrate differing rates of bladder stone formation dependent upon diet. a X-rays of mice with typical bladder stone formation. b 42% of mice on normal chow had bladder stones by 28 weeks, whereas 100% of mice had bladder stones by 28 weeks on breeder chow (N = 12). c X-ray of Slc3a1^−/− animals revealed the development bladder stone formation on breeder chow as depicted by a Kaplan-Meier plot (N = 8)