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Fig. 4 | BMC Nephrology

Fig. 4

From: Metabolic consequences of cystinuria

Fig. 4

Male Slc3a1 −/− mice have higher blood urea nitrogen (BUN) and creatinine indicative of the development of CKD. a Comparison of BUN in wild type (WT) and Slc3a1−/− (KO) animals on a regular or breeder chow diet. KO animals exhibited elevated BUN on both regular and breeder chow when compared to WT animals on the same diet (*, p < 0.05 Mann Whitney test, N = 6–19 ± SEM). b Comparison of serum creatinine in WT and KO animals on a regular or breeder chow diet. KO animals exhibited elevated creatinine on the breeder chow diet but not the regular chow diet (*, p < 0.05, Mann Whitney test, N = 6–19 ± SEM). Each dot on the graph represents an individual measurement from an individual mouse

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