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Table 1 Characteristics of the study sample examining estimated glomerular filtration rate (eGFR)

From: Moderately increased albuminuria, chronic kidney disease and incident dementia: the HUNT study

HUNT 2 (1995–1997)

No dementia

Total Dementia

Combined AD/VaD/Mixed AD/VaD

AD

VaD

Mixed AD/VaD

Other Dementia

P value A

Total study population, n

47,840

668

528

348

112

68

140

 

eGFR, mean (SD)

78.99 (16.15)

63.89 (12.39)

63.13 (12.40)

62.79 (12.12)

64.97 (14.39)

61.88 (9.84)

66.74 (11.91)

.00

4 stages eGFR, n (%)

       

.00

> 90

11,708 (24.5)

16 (2.4)

12 (2.3)

8 (2.3)

4 (3.6)

0

4 (2.9)

 

60.0–89.9

30,347 (63.4)

397 (59.4)

306 (58.0)

196 (56.3)

68 (60.7)

42 (61.8)

91 (65.0)

 

30.0–59.9

5697 (11.9)

251 (37.6)

207 (39.2)

143 (41.1)

38 (33.9)

26 (38.2)

44 (31.4)

 

< 30

88 (.2)

4 (.6)

3 (.6)

1 (.3)

2 (1.8)

0

1 (.7)

 

Diabetes Mellitus, n (%)

1307 (2.7)

34 (5.1)

31 (5.9)

18 (5.2)

8 (7.1)

5 (7.4)

3 (2.1)

.00

Anti-hypertensive tablets, ever, n (%)

6476 (13.5)

211 (31.6)

173 (32.8)

102 (29.3)

48 (42.9)

23 (33.8)

38 (27.1)

.00

Sex, Female, n (%)

25,806 (53.9)

410 (61.4)

341 (64.6)

238 (68.4)

58 (51.8)

45 (66.2)

69 (49.3)

.00

Age at HUNT 2 (1995–1997), mean (SD)

49.24 (16.55)

70.58 (7.54)

71.26 (6.99)

71.62 (6.80)

69.82 (8.19)

71.84 (5.38)

68.02 (8.93)

.00

Time to debut, years, mean (SD)

 

7.15 (3.63)

7.15 (3.65)

7.20 (3.76)

7.41 (3.53)

6.45 (3.16)

7.16 (3.57)

 

Education, n (%)

       

.00

Primary

17,234 (36.0)

458 (68.6)

367 (69.5)

240 (69.0)

77 (68.8)

50 (73.5)

91 (65.0)

 

Completed secondary

26,830 (56.1)

195 (29.2)

151 (28.6)

104 (29.9)

30 (26.8)

17 (25.0)

44 (31.4)

 

Completed upper secondary

3776 (7.9)

15 (2.2)

10 (1.9)

4 (1.1)

5 (4.5)

1 (1.5)

5 (3.6)

 

Cholesterol (mmol/L), mean (SD)

5.87 (1.25)

6.65 (1.24)

6.70 (1.24)

6.72 (1.23)

6.65 (1.5)

6.64 (1.29)

6.46 (1.21)

.00

Non-fasting blood glucose (mmol/L), mean (SD)

5.42 (1.46)

5.88 (1.78)

5.91 (1.79)

5.89 (1.85)

6.03 (1.84)

5.77 (1.37)

5.78 (1.74)

.00

Serum iron (), mean (SD)

16.51 (6.31)

16.08 (5.74)

15.99 (5.79)

16.07 (5.89)

15.55 (5.71)

16.28 (5.55)

16.45 (5.58)

.06

Body Mass Index (kg/m2) mean (SD)

26.32 (4.07)

27.03 (4.11)

26.96 (4.04)

26.76 (4.03)

27.62 (4.39)

26.91 (3.34)

27.28 (4.36)

.00

Pulse (beats/min), mean (SD)

72.96 (12.56)

73.63 (13.87)

73.70 (13.71)

73.77 (14.44)

72.41 (11.77)

75.50 (12.72)

73.36 (14.53)

.21

Systolic BP (mmHg), mean (SD)

136.86 (21.23)

153.27 (23.23)

153.94 (23.52)

153.96 (23.63)

153.63 (22.17)

154.34 (25.34)

150.72 (21.99)

.00

Diastolic BP (mmHg), mean (SD)

80.02 (12.01)

84.68 (12.56)

84.73 (12.56)

83.97 (12.50)

86.47 (12.27)

85.69 (13.13)

84.50 (12.62)

.00

Myocardial Infarction, n (%)

1444 (3.0)

40 (6.0)

32 (6.1)

18 (5.2)

10 (8.9)

4 (5.9)

8 (5.7)

.00

Angina Pectoris, n (%)

2178 (4.6)

90 (13.5)

71 (13.4)

46 (13.2)

15 (13.4)

10 (14.7)

19 (13.6)

.00

Stroke, n (%)

809 (1.7)

25 (3.7)

21 (4.0)

7 (2.0)

12 (10.7)

2 (2.9)

4 (2.9)

.00

Daily Smoker, n (%)

13,425 (28.1)

110 (16.5)

80 (15.2)

44 (12.6)

25 (22.3)

11 (16.2)

30 (21.4)

.00

Subjective health status

       

.00

Poor, n (%)

752 (1.6)

13 (1.9)

12 (2.3)

7 (2.0)

5 (4.5)

0

1 (.7)

 

Not so good, n (%)

11,646 (24.3)

303 (45.4)

239 (45.3)

149 (42.8)

55 (49.1)

35 (51.5)

64 (45.7)

 

Good, n (%)

27,659 (57.8)

323 (48.4)

260 (49.2)

181 (52.0)

47 (42.0)

32 (47.1)

63 (45.0)

 

Very good, n (%)

7783 (16.3)

29 (4.3)

17 (3.2)

11 (3.2)

5 (4.5)

1 (1.5)

12 (8.6)

 
  1. AP-values are derived from t tests for continuous variables and x2 tests for the binary variables comparing means between total dementia and no dementia