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Table 1 Baseline participant characteristics

From: Effect of extended hours dialysis on markers of chronic kidney disease-mineral and bone disorder in the ACTIVE Dialysis study

Characteristics

Standard (n = 100)

Extended (n = 100)

Total (n = 200)

P-value

Mean age at randomization, yr. (SD)

51.6 (11.5)

52.1 (12.7)

51.8 (12.1)

0.79

Male, n (%)

70 (70.0)

69 (69.0)

139 (69.5)

0.88

Country, n (%)

 Australia

28 (28.0)

30 (30.0)

58 (29.0)

0.96

 Canada

6 (6.0)

5 (5.0)

11 (5.5)

 

 China

62 (62.0)

62 (62.0)

124 (62.0)

 

 New Zealand

4 (4.0)

3 (3.0)

7 (3.5)

 

Body Mass Index (kg/m2)

26.7 (6.1)

25.5 (6.4)

26.1 (6.2)

0.16

Number of dialysis sessions per wk., n (%)

 2

1 (1.0)

1 (1.0)

2 (1.0)

0.30

 3

82 (82.0)

86 (86.0)

168 (84.0)

 

  ≥ 4

17 (17.0)

13(13.0)

30 (15.0)

 

Total number of hr. on dialysis per wk

 Median (IQR)

12.4 (12.0–16.0)

12.0 (12.0–15.0)

12.0 (12.0–15.0)

0.10

Duration on dialysis at enrolment, median (IQR) in yr.

2.63 (0.97–6.74)

2.43 (0.67–5.04)

2.48 (0.72–6.00)

0.37

Dialysis site at enrolment, n (%)

 Home

12 (12.0)

11 (11.0)

23 (11.5)

0.83

 In-centre/satellite

88 (88.0)

89 (89.0)

177 (88.5)

 

Intended dialysis site for study treatment, n (%)

 Home

25 (25)

26 (26)

51 (25.5)

0.87

 In-centre/satellite

75 (75.0)

74 (74.0)

149 (74.5)

 

Laboratory parameters, mean (SD)

 Phosphate (mmol/L)

1.77 (0.59)

1.86 (0.53)

1.82 (0.56)

0.31

 PTH (pmol/L) median (IQR)

20.7 (10.9–43.5)

28.5 (11.7–46.2)

24.0 (11.3–46.0)

0.33

 Corrected Calcium (mmol/L)

2.28 (0.24)

2.27 (0.20)

2.28 (0.22)

0.72

 Albumin (g/L)

39.0 (4.5)

39.0 (4.7)

39.0 (4.6)

0.96

Phosphate binder use, n (%)

 Calcium-based

57 (57)

61 (61)

118 (59)

0.28

 Non-calcium based

11 (11)

7 (7)

18 (9)

 

 Both non-calcium and calcium based

12 (12)

6 (6)

18 (9)

 

 No binder

20 (20)

26 (26)

46 (23)

 

Phosphate binder burden (pills/day), median (IQR)

3.5 (1.5–6)

3 (0–6)

3 (1–6)

0.21

Cinacalcet use, n (%)

4 (4.1)

7 (7.0)

11 (5.6)

0.37

Calcitriol and analogues, n (%)

 No vitamin D

45 (46)

48 (48)

93 (47.0)

0.37

 Calcitriol/Alfacalcidiol

47 (48)

49 (49)

96 (48.5)

 

 Cholecalciferol

6 (6)

2 (2)

8 (4.0)

 

 Both

0 (0)

1 (1)

1 (0.5)

 

Dialysate calcium (mmol/L), n (%)

 Low (≤1.3)

36 (36.0)

32 (32.0)

68 (34.0)

0.63

 Mid (1.5)

58 (58.0)

64 (64.0)

122 (61.0)

 

 High (≥1.6)

6 (6.0)

4 (4.0)

10 (5.0)