Ambulatory monitoring unmasks hypertension among kidney transplant patients: single center experience and review of the literature

Table 5 Associations of the clinic-awake BP differences (ΔBP) with clinical variables

Parameter	ΔSBP		ΔDBP
Parameter	Coefficient	P-value	Coefficient	P-value
Age > 60 years	−9.2	0.026	− 1.2	0.624
BMI, kg/m²	0.3	0.402	−0.1	0.722
Diabetes	0.2	0.964	3.0	0.231
Past smoking vs. never	−0.5	0.929	−4.7	0.179
Type of allograft, cadaveric vs. alive	0.7	0.874	2.5	0.324
Time since transplantation, years	0.1	0.614	−0.03	0.809
eGFR (CKD-EPI), ml/min/1.73m²	−0.1	0.171	0.01	0.855
Creatinine clearance, ml/min	−0.1	0.302	0.02	0.525
Urine protein excretion, mg/d (log₁₀)	−0.3	0.956	2.4	0.364
Hemoglobin, g/dl	−1.3	0.244	0.2	0.697
Anti-hypertensive medications (any)	6.1	0.173	1.6	0.532
ACEi or ARBs	3.4	0.393	−0.2	0.915
Beta blockers	0.8	0.847	2.1	0.358
Calcium channel blockers	−0.2	0.968	0.2	0.947
Diuretics	−3.4	0.521	−2.7	0.365
Alpha blockers	−2.3	0.727	0.9	0.815
No. of antihypertensive medications	−0.3	0.800	−0.2	0.798
Aspirin	−0.1	0.984	3.0	0.242
Tacrolimus vs. cyclosporine	−10.1	0.046	−1.8	0.546
Non-CNI vs. cyclosporine	−16.3	0.038	−3.5	0.446
Siesta	4.7	0.441	0.5	0.892
Oscillometric vs. aneroid clinic measurement	7.0	0.146	3.7	0.177
Clinic BP, mmHg	0.4	0.003	0.4	< 0.001
SD of awake ambulatory BP, mmHg	−1.0	0.034	−0.7	0.076

Abbreviations: BMI Body mass index, eGFR Estimated glomerular filtration rate, CKD-EPI Chronic Kidney Disease Epidemiology Collaboration, ACEi Angiotensin converting enzyme inhibitor, ARBs Angiotensin receptor blocker, CNI Calcineurin inhibitor, BP Blood pressure, SD Standard deviation
Bold entries are significant

ISSN: 1471-2369