Table 2 Biologic profile and stage of chronic kidney disease of study participants at referral
Biologic Data | Total | Gender | P | Stage | P | ||||
|---|---|---|---|---|---|---|---|---|---|
Male | Female | G3a | G3b | G4 | G5 | ||||
Blood urea nitrogen (g/l)h | 1.12 (0.7–2.1) | 1.1 (0.7–2.0) | 1.3 (0.7–2.2) | 0.918 | 0.4 (0.3–0.6) | 0.7 (0.5–1.2) | 0.8 (0.6–1.1) | 1.8 (1.05–2.5) | < 0.001 |
Serum Creatinine (mg/l)h | 67.7 (29.3–118.5) | 73.4 (29.6–101.3) | 61.9 (28.4–135.1) | 0.457 | 16.7 (15.8–19.6) | 24.7 (21–25.4) | 33.9 (29.6–40.6) | 103 (79.8–160.9) | < 0.001 |
GFRa (ml/min/1.73 m2)h | 10.1 (4.7–27.2) | 10.2 (6.5–31.5) | 9.5 (3.4–23.3) | 0.028 | 49.5 (47.9–51.8) | 37.1 (31.9–40.5) | 22.4 (19.8–26.51) | 5.3 (3.2–8.3) | < 0.001 |
CKDb stage, n (%) |  |  |  |  | – | – | – | – |  |
 G1 | 0 (0.0) | 0 (0.0) | 0 (0.0) |  | – | – | – | – |  |
 G2 | 0 (0.0) | 0 (0.0) | 0 (0.0) |  | – | – | – | – |  |
 G3a | 13 (8.3) | 8 (10.0) | 5 (6.6) |  | – | – | – | – |  |
 G3b | 20 (12.8) | 13 (16.3) | 7 (9.2) |  | – | – | – | – |  |
 G4 | 32 (20.5) | 17 (21.3) | 15 (19.7) |  | – | – | – | – |  |
 G5 | 91 (58.3) | 42 (52.5) | 49 (64.5) | 0.383 | – | – | – | – |  |
Urinary dipstick, n (%) | |||||||||
 Proteinuria | 121 (77.6) | 65 (81.3) | 56 (73.7) | 0.258 | 7 (53.8) | 15 (75.0) | 27 (84.4) | 72 (79.1) | 0.154 |
 Hematuria | 42 (26.9) | 26 (32.5) | 16 (21.1) | 0.107 | 2 (15.4) | 5 (25.0) | 5 (15.6) | 30 (33.3) | 0.183 |
 Leucocyturia | 23 (14.7) | 10 (12.5) | 13 (17.1) | 0.417 | 1 (7.7) | 3 (15.0) | 3 (9.4) | 16 (17.8) | 0.594 |
 Glycosuria | 10 (6.4) | 5 (6.3) | 5 (6.6) | 0.933 | 0 (0.0) | 1 (5.0) | 2 (6.3) | 7 (7.8) | 0.746 |
Lipid profile, Mean ± SD | |||||||||
 Total cholesterol (g/l) | 1.8 ± 0.6 | 1.7 ± 0.5 | 2.0 ± 0.7 | 0.109 | 1.7 ± 0.3 | 1.9 ± 0.5 | 2.1 ± 0.7 | 1.8 ± 0.6 | 0.551 |
 LDLc cholesterol (g/l) | 1.0 ± 0.6 | 1.0 ± 0.6 | 1.1 ± 0.7 | 0.668 | 0.4 ± 0.2 | 0.3 ± 0.2 | 0.5 ± 0.2 | 0.4 ± 0.2 | 0.214 |
 HDLd cholesterol (g/l) | 0.4 ± 0.2 | 0.3 ± 0.1 | 0.4 ± 0.2 | 0.064 | 0.6 ± 0.2 | 1.0 ± 0.1 | 1.1 ± 0.7 | 1.0 ± 0.7 | 0.825 |
 Triglycerides (g/l) | 1.8 ± 1.1 | 1.6 ± 0.8 | 2.0 ± 1.3 | 0.317 | 2.3 ± 0.2 | 1.6 ± 2.1 | 1.7 ± 0.9 | 1.9 ± 0.9 | 0.857 |
Hemoglobin (g/dl), Mean ± SD | 8.2 ± 2.3 | 8.7 ± 2.4 | 7.6 ± 1.9 | 0.002 | 9.8 ± 3.3 | 9.0 ± 2.2 | 8.5 ± 2.2 | 7.7 ± 2.0 | 0.004 |
Anemia, n = 148, n (%) | 139 (93.9) | 68 (90.7) | 71 (97.3) | 0.167 | 9 (75.0) | 18 (90.0) | 29 (93.5) | 84 (97.7) | 0.017 |
MCVe (fl), n = 107 | |||||||||
 Mean ± SD | 85.5 ± 9.8 | 85.9 ± 9.4 | 85.1 ± 10.2 | 0.674 | 85.5 ± 9.8 | 85.8 ± 8.1 | 85.3 ± 7.9 | 85.4 ± 10.7 | 0.999 |
 < 80 | 34 (31.8) | 17 (31.5) | 17 (32.1) |  | 3 (50.0) | 4 (30.8) | 6 (30.0) | 21 (30.9) |  |
 > 100 | 8 (7.5) | 4 (7.4) | 4 (7.5) | 0.997 | 0 (0.0) | 0 (0.0) | 1 (5.0) | 7 (10.3) | 0.765 |
MCHf (pg), n = 100 | |||||||||
 Mean ± SD | 28.1 ± 4.3 | 28.0 ± 5.0 | 28.1 ± 3.5 | 0.885 | 29.2 ± 3.6 | 28.6 ± 3.8 | 27.6 ± 3.3 | 28.3 ± 4.0 | 0.791 |
 < 28 | 48 (48.0) | 22 (45.8) | 26 (50.0) |  | 3 (50.0) | 6 (46.2) | 11 (57.9) | 28 (45.2) |  |
 > 32 | 15 (15.0) | 8 (16.7) | 7 (13.5) | 0.875 | 2 (33.3) | 2 (15.4) | 2 (10.5) | 9 (14.5) | 0.793 |
WBCg (G/l)h, n = 124 | |||||||||
 Median (1st-3th quartiles) | 5.3 (4.1–7.1) | 5.3 (4.4–7.2) | 5.1 (3.9–7.1) | 0.276 | 4.9 (4.2–5.3) | 5.3 (3.8–8.8) | 5.2 (4–8) | 5.4 (4.1–7.1) | 0.843 |
 < 4 | 25 (20.7) | 9 (15.0) | 16 (26.2) |  | 0 (0.0) | 5 (31.3) | 5 (21.7) | 15 (20.3) |  |
 > 10 | 12 (9.9) | 5 (8.3) | 7 (11.5) | 0.218 | 0 (0.0) | 1 (6.3) | 1 (4.3) | 10 (13.5) | 0.314 |
Platelets (G/l), n = 121 | |||||||||
 Mean ± SD | 223.4 ± 94.1 | 214.6 ± 93.0 | 232.4 ± 95.2 | 0.300 | 224.3 ± 112.5 | 213.5 ± 85.4 | 214.4 ± 91.6 | 223.6 ± 93.6 | 0.877 |
 < 150 | 25 (20.7) | 16 (26.2) | 9 (15.0) | 0.267 | 2 (22.2) | 2 (11.1) | 5 (20.8) | 16 (22.5) | 0.511 |
Natremia (mmol/l), n = 111 | |||||||||
 Mean ± SD | 135.0 ± 8.8 | 134.6 ± 9.1 | 135.4 ± 8.6 | 0.639 | 136.1 ± 6.5 | 134.9 ± 6.1 | 136.8 ± 10.1 | 134.3 ± 9.2 | 0.718 |
 < 135 | 44 (39.6) | 23 (40.4) | 21 (38.9) | 0.571 | 5 (55.6) | 5 (38.5) | 4 (19.0) | 31 (44.9) | 0.393 |
Potassium (mmol/l), n = 109 | |||||||||
 Mean ± SD | 5.3 ± 3.3 | 5.0 ± 0.98 | 4.9 ± 1.2 | 0.726 | 4.2 ± 0.5 | 4.8 ± 0.9 | 4.8 ± 0.8 | 5.1 ± 1.2 | 0.096 |
 < 3.5 | 4 (3.7) | 2 (3.6) | 2 (3.7) |  | 0 (0.0) | 0 (0.0) | 1 (5.0) | 3 (4.3) |  |
 > 5.0 | 47 (43.1) | 27 (49.1) | 20 (37.0) | 0.437 | 1 (11.1) | 6 (50.0) | 10 (50.0) | 30 (43.5) | 0.435 |
Chloremia (mmol/l), n = 101 | |||||||||
 Mean ± SD | 101.7 ± 9.4 | 101.0 ± 9.7 | 102.6 ± 8.9 | 0.410 | 99.1 ± 10.3 | 103.8 ± 11.5 | 103.1 ± 7.2 | 101.3 ± 9.4 | 0.631 |
 < 95 | 25 (24.8) | 14 (25.5) | 11 (23.9) |  | 3 (37.5) | 3 (25.0) | 3 (17.6) | 16 (24.6) |  |
 > 105 | 33 (32.7) | 15 (27.3) | 18 (39.1) | 0.421 | 2 (25.0) | 6 (50.0) | 5 (29.4) | 20 (30.6) | 0.724 |
Calcemia (mg/l), n = 102 | |||||||||
 Mean ± SD | 84.6 ± 13.7 | 87.5 ± 15.3 | 81.5 ± 11.1 | 0.024 | 84.6 ± 8.8 | 89.9 ± 10.5 | 87.5 ± 10.0 | 83.1 ± 15.1 | 0.413 |
 < 90 | 70 (68.6) | 31 (60.8) | 39 (76.5) |  | 5 (62.5) | 5 (55.6) | 8 (47.1) | 52 (75.4) |  |
 > 105 | 2 (2.0) | 2 (3.9) | 0 (0.0) | 0.128 | 0 (0.0) | 1 (11.1) | 0 (0.0) | 1 (1.4) | 0.102 |
Phosphoremia (mg/l), n = 89 | |||||||||
 Mean ± SD | 56.6 ± 31.5 | 50.8 ± 26.4 | 62.3 ± 35.1 | 0.086 | 38.2 ± 19.3 | 36.6 ± 8.5 | 49.9 ± 28.2 | 62.1 ± 33.2 | 0.056 |
 < 35 | 22 (24.7) | 12 (27.3) | 10 (22.2) |  | 2 (33.3) | 5 (71.4) | 5 (35.7) | 10 (16.1) |  |
 > 55 | 32 (36.0) | 11 (25.0) | 21 (46.7) | 0.096 | 1 (16.7) | 0 (0.0) | 3 (21.4) | 28 (45.2) | 0.022 |
Uricemia (mg/l), n = 66 | |||||||||
 Mean ± SD | 89.3 ± 32.2 | 91.7 ± 33.2 | 88.7 ± 31.4 | 0.530 | 78.1 ± 16.1 | 78.5 ± 24.2 | 88.4 ± 35.2 | 93.8 ± 34.2 | 0.509 |
 > 70 | 50 (75.8) | 27 (79.4) | 23 (71.9) | 0.515 | 5 (83.3) | 6 (75.0) | 11 (73.3) | 28 (75.7) | 0.982 |
Albuminemia (g/l), n = 80 | |||||||||
 Mean ± SD | 32.8 ± 11.2 | 33.5 ± 13.9 | 31.9 ± 7.5 | 0.531 | 34.0 ± 2.9 | 29.7 ± 7.2 | 37.3 ± 18.4 | 31.7 ± 9.0 | 0.294 |
 < 35 | 51 (63.7) | 27 (65.9) | 24 (61.5) | 0.688 | 3 (60.0) | 6 (75.0) | 9 (56.3) | 34 (65.4) | 0.822 |