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Table 4 Bivariate correlation between bone-related biomarkers and spine BMD

From: Serum sclerostin levels are positively related to bone mineral density in peritoneal dialysis patients: a cross-sectional study

 

BMD, spine L1 to L4

BMD, spine T-score

BMD, spine Z-score

Parameters

rs

P value

adjusted rs

P value

rs

P value

adjusted rs

P value

rs

P value

adjusted rs

P value

Age (year)

−0.225

0.034

  

−0.245

0.021

  

0.124

0.248

  

Sex-male

0.184

0.085

  

0.006

0.955

  

−0.017

0.877

  

Sclerostin (pmol/L)

0.277

0.009

0.271

0.011

0.237

0.025

0.274

0.010

0.232

0.029

0.237

0.027

FGF-23 (pg/mL)

0.124

0.248

0.049

0.650

0.093

0.386

0.060

0.579

−0.018

0.866

0.004

0.969

DKK-1 (pg/mL)

0.017

0.876

−0.022

0.838

0.020

0.852

−0.008

0.937

−0.101

0.347

−0.087

0.423

CTX (ng/mL)

−0.080

0.455

−0.051

0.642

−0.087

0.419

−0.055

0.610

−0.118

0.272

−0.137

0.205

Osteocalcin (ng/mL)

−0.199

0.062

−0.273

0.010

−0.202

0.057

−0.254

0.017

−0.352

< 0.001

−0.339

0.001

Intact PTH (pg/mL)

−0.192

0.072

−0.242

0.024

−0.202

0.058

−0.220

0.041

−0.291

0.006

−0.291

0.006

Alkaline phosphatase (U/L)

−0.201

0.059

−0.120

0.268

−0.184

0.085

−0.120

0.270

−0.150

0.160

−0.201

0.062

  1. rs Spearman rank correlation coefficient, adjusted rs partial correlation coefficient adjusted for age and gender, FGF-23 fibroblast growth factor 23; DKK-1 dickkopf-1, CTX crosslinked C-telopeptide of type 1 collagen, PTH parathyroid hormone, BMD bone mineral density
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BMC Nephrology

ISSN: 1471-2369

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