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Table 1 Demographics and laboratory values. The degree of presence of nephrospheres in urine was determined according to observations of two independent examiners. Estimated glomerular filtration rate (eGFR), blood urea nitrogen (BUN), C-reactive protein (CRP), acute kidney injury (AKI), atypical hemolytic uremic syndrome (aHUS), thrombotic microangiopathy (TMA)

From: Urinary nephrospheres indicate recovery from acute kidney injury in renal allograft recipients – a pilot study

 

Transplanted (n = 45)

Non-transplanted (n = 19)

p-value

Female—no. (%)

14 (31.12)

11 (57.89)

p = 0.055

Age [years]

59.02 ± 13.51

58.95 ± 21.70

p = 0.988

Serum Creatinine [mg/dL]

4.152 ± 2.460

3.749 ± 1.635

p = 0.516

eGFR [ml/min/1.73m2]

23.76 ± 17.98

19.71 ± 11.33

p = 0.368

BUN [mg/dl]

45.667 ± 27.654

51.818 ± 18.331

p = 0.378

CRP [mg/dl]

4.395 (1.052;9.46)*

5.190 (0.84;10.98)*

p = 0.371

Degree of presence of nephrospheres in urine—no. (%)

 None

28 (62.2)

19 (100)

p < 0.001

 Low

9 (20.0)

0 (0)

p = 0.048

 Medium

4 (8.9)

0 (0)

p = 0.309

 High

4 (8.9)

0 (0)

p = 0.309

Reasons for AKI—no. (%)

 Infection

21 (46.7)

8 (42.1)

p = 0.789

 Ischemia

10 (22.2)

3 (15.8)

p = 0.738

 Chemotherapy

2 (4.4)

4 (21.1)

p = 0.058

 Heart failure

5 (11.1)

3 (15.8)

p = 0.685

 aHUS/TMA

3 (6.7)

1 (5.3)

p = 0.999

 Graft rejection

3 (6.7)

0 (0)

p = 0.548

 Postrenal causes

1 (2.2)

0 (0)

p = 0.999

  1. * = median (upper quartile;lower quartile); numbers in bold represent statistical significant values