Skip to main content

Table 1 Baseline characteristics of studied population undergoing cardiac surgery

From: Urine klotho is a potential early biomarker for acute kidney injury and associated with poor renal outcome after cardiac surgery

 

All (n = 91)

AKI (n = 33)

Non-AKI (n = 58)

p value

Preoperative condition

 Male, n (%)

58 (63.7%)

23 (69.7%)

35 (63.7%)

0.372

 Age (year)a

61.79 ± 9.37

64.15 ± 9.37

60.45 ± 9.18

0.070

 Weight (kg)a

62.11 ± 10.29

63.36 ± 10.06

61.38 ± 10.45

0.384

 Hypertension, n (%)

33 (36.3%)

13 (39.4%)

20 (34.5%)

0.639

 Diabetes, n (%)

14 (15.4%)

6 (18.2%)

8 (13.8%)

0.577

 Hyperuricemia, n (%)

15 (16.5%)

6 (18.2%)

9 (15.5%)

0.742

 Cerebrovascular disease, n (%)

4 (4.4%)

0 (0.0%)

4 (6.9%)

0.312

 Hyperlipidemia, n (%)

6 (6.6%)

1 (3.0%)

5 (8.6%)

0.553

 Peripheral vascular disease, n (%)

3 (3.3%)

2 (6.1%)

1 (1.7%)

0.615

 Congestive heart failure, n (%)

13 (14.3%)

7 (21.2%)

6 (10.3%)

0.266

 Contrast medium, n (%)

14 (15.4%)

7 (21.2%)

7 (12.1%)

0.245

 Use of ACE inhibitors/ARBs, n (%)

25 (27.5%)

9 (27.3%)

16 (27.6%)

0.974

 Hemoglobin (g/L)b

129.00

(116.00, 141.00)

124.00

(113.00, 141.00)

133.00

(120.00, 141.50)

0.219

 Scr (umol/L)a

73.77 ± 13.88

76.09 ± 15.60

72.44 ± 12.76

0.230

 eGFR (ml/min/1.73m2)a

86.89 ± 15.55

88.38 ± 14.35

84.27 ± 17.37

0.228

Intraoperative condition

 Type of surgery

 CABG, n (%)

32 (35.2%)

10 (30.3%)

22 (37.9%)

0.464

 Single valve, n (%)

20 (22.0%)

6 (18.2%)

14 (24.1%)

0.509

 Double valve, n (%)

19 (20.0%)

9 (27.3%)

10 (17.2%)

0.258

 CABG plus valve surgery, n (%)

10 (11.0%)

4 (12.1%)

6 (10.3%)

1.000

 CHD, n (%)

5 (5.5%)

2 (6.1%)

3 (5.2%)

1.000

 Aortic aneurysm surgery, n (%)

5 (5.5%)

2 (6.1%)

3 (5.2%)

1.000

 CPB, n (%)

67 (73.6%)

27 (81.8%)

40 (70.2%)

0.222

 Operation time, hb*

5.00 (4.00, 6.00)

5.50 (4.50, 6.25)

4.50 (4.00, 5.50)

0.002

 CPB time (min)b

84.00 (0.00, 115.00)

94.00 (56.00, 134.00)

76.50 (0.00, 112.25)

0.223

 AXC time (min)b

46.00 (0.00, 69.00)

55.00 (11.50, 73.50)

46.00 (0.00, 66.50)

0.537

 Cardiac arrest time (min)b

48.00 (0.00, 74.00)

60.00 (13.00, 75.00)

46.50 (0.00, 70.00)

0.526

 Transfusion > 400 ml, n (%)

10 (11.0%)

4 (12.1%)

6 (10.3%)

1.000

  1. aData were presented as means ± standard deviation (SD) and the difference were calculated using t test. bData were presented as medians (IOR, interquartile range) and were analyzed using non-parametric Mann-Whitney U test. Categorical variables were presented as number (percentage of the column total) and were analyzed using Pearson χ2 test. *p < 0.05
  2. ACE Angiotensin-converting enzyme, ARB Angiotensin receptor blockers, SCr Serum creatinine, eGFR Estimated glomerular filtration rate, CABG Coronary artery bypass grafting, CHD Congenital heart disease, CPB Cardiopulmonary bypass, AXC Aortic cross clamp