Spot urine protein/creatinine ratio as a reliable estimate of 24-hour proteinuria in patients with immunoglobulin A nephropathy, but not membranous nephropathy

Table 1 Patients’ characteristics

	All cases N = 161	IgAN N = 84	MCD N = 53	MGN-NS N = 24	P values (by ANOVA)
Age, years	44.9 ± 18.9	40.0 ± 15.9	43.5 ± 20.3	65.0 ± 10.8	< 0.001
Male, n (%)	91 (56.5)	43 (51.2)	31 (58.5)	17 (70.8)	0.217
Creatinine, mg/dL	1.10 ± 0.87	0.95 ± 0.40	1.32 ± 1.30	1.11 ± 0.84	0.051
eGFR, mL/min/1,73 m²	69.8 ± 27.6	72.2 ± 24.9	69.1 ± 32.5	62.7 ± 24.5	0.326
Spot urinary protein, mg/dL	749 ± 1148	129 ± 152	1506 ± 1315	1249 ± 1483	< 0.001
Spot urinary creatinine, mg/dL	151 ± 125	115 ± 93	207 ± 155	153 ± 110	< 0.001
24-h urinary creatinine, g/day	1.17 ± 0.47	1.23 ± 0.4	1.16 ± 0.49	1.00 ± 0.29	0.1
24-h urinary protein, mg/dL	466 ± 704	84 ± 92	1028 ± 867	560 ± 668	< 0.001
Daily urinary protein, g/day	4.32 ± 4.51	1.22 ± 1.24	8.44 ± 4.88	6.00 ± 2.29	< 0.001
24-h urine volume, mL/day	1502 ± 769	1655 ± 711	1242 ± 809	1537 ± 750	0.008

Data are expressed as means ± standard deviation or numbers (%). IgAN denotes immunoglobulin A nephropathy, MCD minimal change disease, MGN-NS Membranous glomerulonephritis with nephrotic syndrome, ANOVA analysis of variance, eGFR estimated glomerular filtration rate

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