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Table 2 Hb levels, ESA and IV iron doses, anemia- and volume status-related parameters

From: Usefulness of mid-week hemoglobin measurement for anemia management in patients undergoing hemodialysis: a retrospective cohort study

 

Early-week days

Mid-week days

P-value

Hb (g/dL)

10.71 ± 0.06

10.78 ± 0.47

0.105

Hct (%)

33.83 ± 12.36

32.36 ± 1.53

0.230

Dose of ESA (μg/month) a

175.4 ± 72.5

163.7 ± 83.6

0.022

 Median (range)

170.0 (0–376.7)

157.1 (13.3–492.5)

 

 Interquartile range

123.5–201.9

108.0–208.8

 

Dose of IV iron (mg/year) b

623.0 ± 489.0

447.0 ± 505.2

0.001

Parameters related to volume status

 Interdialytic body weight gain (kg)

2.81 ± 0.82

1.99 ± 0.61

< 0.001

 Ultrafiltration volume (kg)

2.65 ± 0.73

2.12 ± 0.66

< 0.001

 Pre-dialysis body weight/DBW (%)

104.89 ± 3.42

103.51 ± 1.77

< 0.001

Parameters related to anemia

 spKt/V

1.63 ± 0.24

1.67 ± 0.23

< 0.001

 Albumin (g/dL)

3.62 ± 0.74

3.76 ± 0.80

< 0.001

 Prealbumin (mg/dL)

34.05 ± 7.01

31.94 ± 6.84

< 0.001

 hs-CRP (mg/L)

0.26 ± 0.33

0.28 ± 0.33

0.151

 Ferritin (ng/mL)

386.0 ± 292.4

308.1 ± 238.0

< 0.001

 TSAT (%)

36.43 ± 9.03

37.46 ± 10.90

0.304

 iPTH (pg/mL)

205.1 ± 113.7

230.4 ± 129.9

0.021

  1. Values are given as mean ± standard deviation unless otherwise indicated
  2. a darbepoetin alfa. b iron hydroxide sucrose
  3. Hb, hemoglobin; Hct, hematocrit; ESA, erythropoiesis-stimulating agent; IV, intravenous; DBW, dry body weight; spKt/V, single pool Kt/V; hs-CRP, high-sensitivity C-reactive protein; TSAT, transferrin saturation; iPTH, intact parathyroid hormone