Use of estimated glomerular filtration rate to predict incident chronic kidney disease in patients at risk of cardiovascular disease: a retrospective study

Table 1 Comparison of baseline characteristics according to the development of CKD stages 3–5

Characteristic	Total (n = 622)	CKD^a (n = 71)	No CKD^a (n = 551)	P value^b
Age (years)	52.38 ± 14.48	63.35 ± 9.49	50.96 ± 14.41	< 0.001
Male sex, n (%)	312 (50.2)	41 (57.7)	271 (49.2)	0.207
History of, n (%)
CVD	87 (14.0)	26 (36.6)	61 (11.1)	< 0.001
Smoking	92 (14.8)	15 (21.1)	77 (14.0)	0.112
Obesity	294 (47.3)	38 (53.5)	256 (46.5)	0.312
DM	197 (31.7)	48 (67.6)	149 (27.0)	< 0.001
HTN	368 (59.2)	60 (84.5)	308 (55.9)	< 0.001
Dyslipidemia	318 (51.1)	54 (76.1)	264 (47.9)	< 0.001
Anthropometric values
BMI (kg/m²)	30.40 ± 6.28	30.26 ± 5.95	30.41 ± 6.33	0.847
SBP (mmHg)	131.73 ± 16.46	136.83 ± 18.45	131.07 ± 16.09	0.005
DBP (mmHg)	77.30 ± 11.44	74.55 ± 12.38	77.65 ± 11.28	0.031
Laboratory values
TC (mmol/L)	5.00 (4.30, 5.80)	4.40 (3.90, 5.45)	5.00 (4.30, 5.80)	0.004
TG (mmol/L)	1.11 (0.79, 1.65)	1.35 (1.01, 1.89)	1.09 (0.78, 1.61)	0.002
SCr (μmol/L)	67.44 ± 17.80	82.29 ± 17.04	65.53 ± 16.99	< 0.001
eGFR (mL/min/1.73 m²)	98.99 ± 19.36	78.39 ± 11.58	101.65 ± 18.55	< 0.001
HbA1c (%)	6.10 (5.60, 6.96)	7.30 (6.45, 9.25)	6.00 (5.59, 6.70)	< 0.001

CVD cardiovascular disease, DM diabetes mellitus, HTN hypertension, BMI body mass index, eGFR estimated glomerular filtration rate, SBP systolic blood pressure, DBP diastolic blood pressure, SCr serum creatinine, TC total cholesterol, TG triglycerides, HbA1c glycosylated hemoglobin A1C
Data are reported as mean ± standard deviation or percent or median (1st, 3rd quartile)
^aChronic kidney disease stages 3–5
^bIndependent samples t-test was used to calculate P values for continuous variables and Fisher’s exact test (two-tailed) for categorical variables. The Mann-Whitney U-test was used to compare the median values of TC, TG, and HbA1c

ISSN: 1471-2369